The female larval fly CNS connectome: first draft
- 1MRC LMB
Abstract
We release an enhanced FIB-SEM volume and associated neuron, mitochondria, synapse and glia automated segmentations for the complete, gap- and artifact-free central nervous system of the first instar female larval Drosophila melanogaster. Segmentation data is largely unproofread besides select neurons in the premotor and proprioceptive system and select subvolumes where synapses have been manually annotated, serving as training and evaluation data. The dataset represents the first complete central nervous system of the larval fly, and now awaits substantial improvement of machine vision approaches that effectively leverage domain knowledge for the automated yet data-guided proofreading, or substantial and costly human proofreading. All the data and methods are publicly available for further improvement and analysis.
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BibTeX
@misc{mohinta2026female,
title = {{The female larval fly CNS connectome: first draft}},
author = {S. Mohinta and D. Franco-Barranco and S. Y. Lee and P. Gomez-Galvez and S. Agrawal and M. Clayton and C. L. Barnes and N. Randel and A. Correia and N. Ceffa and N. S. Velichkova and K. Nielsen and H. Hess and S. Pang and C. S. Xu and J. Berni and M. Januszewski and M. Zlatic and A. Cardona},
howpublished = {bioRxiv},
year = {2026},
month = sep,
doi = {10.64898/2026.09.28.754924},
url = {https://www.biorxiv.org/content/10.64898/2026.09.28.754924v1},
note = {CC BY},
}
RIS
TY - UNPB
TI - The female larval fly CNS connectome: first draft
AU - S. Mohinta
AU - D. Franco-Barranco
AU - S. Y. Lee
AU - P. Gomez-Galvez
AU - S. Agrawal
AU - M. Clayton
AU - C. L. Barnes
AU - N. Randel
AU - A. Correia
AU - N. Ceffa
AU - N. S. Velichkova
AU - K. Nielsen
AU - H. Hess
AU - S. Pang
AU - C. S. Xu
AU - J. Berni
AU - M. Januszewski
AU - M. Zlatic
AU - A. Cardona
PY - 2026
DA - 2026/09/28
PB - bioRxiv
DO - 10.64898/2026.09.28.754924
UR - https://www.biorxiv.org/content/10.64898/2026.09.28.754924v1
AB - We release an enhanced FIB-SEM volume and associated neuron, mitochondria, synapse and glia automated segmentations for the complete, gap- and artifact-free central nervous system of the first instar female larval Drosophila melanogaster. Segmentation data is largely unproofread besides select neurons in the premotor and proprioceptive system and select subvolumes where synapses have been manually annotated, serving as training and evaluation data. The dataset represents the first complete central nervous system of the larval fly, and now awaits substantial improvement of machine vision approaches that effectively leverage domain knowledge for the automated yet data-guided proofreading, or substantial and costly human proofreading. All the data and methods are publicly available for further improvement and analysis.
ER -