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Peer-reviewedCC BY 4.0Mathematics

SAG-RS: Trajectory-Aware Probability Stacking with Contextual-Bandit Reliability Gating for ICD-Audited Diabetes Phenotype Identification in MIMIC-IV

  1. 1College of Information Science and Engineering, Hunan Women’s University, Changsha 410004, China
  2. 2College of Computer Science and Electronic Engineering, Hunan University, Changsha 410082, China

Abstract

Background: Identifying diabetes phenotypes in electronic health records is challenging when repeated admissions and diagnosis-derived variables can bias evaluation. Methods: We reconstructed an ICD-audited diabetes phenotype from MIMIC-IV v3.1 and compared LightGBM with trajectory-aware probability stacking and a conservative contextual-bandit reliability gate. Patient-level separation, out-of-fold feature generation, independent gate development, and a common upstream Base model were used. Results: On the primary held-out split (51,400 records), Full SAG-RS achieved accuracy 0.926654, F1 0.889579, AUC 0.961288, and Brier 0.059649. Across five patient-level splits, mean accuracy was 0.928021 ± 0.002217. The gate improved primary-split accuracy over Stack-only by 0.000233 (95% paired confidence interval −0.000078 to 0.000548); net corrections were positive in three of five splits. Conclusions: Trajectory-aware stacking provided most of the gain over admission-level LightGBM. The gate offered limited, variable correction rather than a demonstrated independent performance gain. Findings are restricted to retrospective internal validation; external validation and full-pipeline replication remain outstanding.

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BibTeX
@article{lv2026sagrs,
  title = {{SAG-RS: Trajectory-Aware Probability Stacking with Contextual-Bandit Reliability Gating for ICD-Audited Diabetes Phenotype Identification in MIMIC-IV}},
  author = {Hongchao Lv and Yineng Chen and Qingshan Ren and Shukun Liu and Xianghua Peng and Chengkai Chen and Yixin Zhang},
  journal = {Mathematics},
  year = {2026},
  month = nov,
  doi = {10.3390/math14213978},
  url = {https://www.mdpi.com/2227-7390/14/21/3978},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - SAG-RS: Trajectory-Aware Probability Stacking with Contextual-Bandit Reliability Gating for ICD-Audited Diabetes Phenotype Identification in MIMIC-IV
AU  - Hongchao Lv
AU  - Yineng Chen
AU  - Qingshan Ren
AU  - Shukun Liu
AU  - Xianghua Peng
AU  - Chengkai Chen
AU  - Yixin Zhang
PY  - 2026
DA  - 2026/11/01
JO  - Mathematics
DO  - 10.3390/math14213978
UR  - https://www.mdpi.com/2227-7390/14/21/3978
AB  - Background: Identifying diabetes phenotypes in electronic health records is challenging when repeated admissions and diagnosis-derived variables can bias evaluation. Methods: We reconstructed an ICD-audited diabetes phenotype from MIMIC-IV v3.1 and compared LightGBM with trajectory-aware probability stacking and a conservative contextual-bandit reliability gate. Patient-level separation, out-of-fold feature generation, independent gate development, and a common upstream Base model were used. Results: On the primary held-out split (51,400 records), Full SAG-RS achieved accuracy 0.926654, F1 0.889579, AUC 0.961288, and Brier 0.059649. Across five patient-level splits, mean accuracy was 0.928021 ± 0.002217. The gate improved primary-split accuracy over Stack-only by 0.000233 (95% paired confidence interval −0.000078 to 0.000548); net corrections were positive in three of five splits. Conclusions: Trajectory-aware stacking provided most of the gain over admission-level LightGBM. The gate offered limited, variable correction rather than a demonstrated independent performance gain. Findings are restricted to retrospective internal validation; external validation and full-pipeline replication remain outstanding.
SN  - 2227-7390
ER  -