Fetal Echocardiography After a Normal Anatomy Assessment: A Retrospective Cohort of In Vitro Fertilization Pregnancies.
4 affiliations
- 1Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota, Minneapolis, Minnesota, USA.
- 2University of Minnesota Medical School, Minneapolis, Minnesota, USA.
- 3Biostatistics Core, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.
- 4Division of Pediatric Cardiology, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Abstract
Purpose
To investigate the detection rate of congenital heart disease (CHD) on fetal echocardiogram after a normal and complete detailed fetal ultrasound among pregnancies conceived by in vitro fertilization (IVF).Methods
This retrospective cohort study examined singleton IVF pregnancies that underwent a detailed fetal anatomic survey without any identified abnormalities, followed by fetal echocardiogram. The primary outcome was the rate of CHD diagnosis after normal and complete anatomic ultrasound. Patients with multifetal gestation, pre-gestational diabetes, a known family history of CHD, fetal abnormalities on anatomy ultrasound, or patients who had an incomplete initial anatomy ultrasound were excluded. Prenatal CHD was confirmed with neonatal imaging and infants were followed after birth.Results
300 pregnancies were included, and of these 266 had a normal and complete anatomy ultrasound. 1.5% (n = 4) of pregnancies had minor CHD identified on fetal echocardiography which was not identified on the anatomy ultrasound. None of the infants required cardiac-related interventions in the first year of life.Conclusion
No major CHD was identified at fetal echocardiography after a normal and complete anatomic survey. Our results support the American Institute of Ultrasound in Medicine guidelines that state a dedicated fetal echocardiogram may be considered, but is not recommended, for singleton IVF pregnancies.
Related
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BibTeX
@article{dickson2026fetal,
title = {{Fetal Echocardiography After a Normal Anatomy Assessment: A Retrospective Cohort of In Vitro Fertilization Pregnancies.}},
author = {Brianna Dickson and Hannah Maher and Savannah Maynard and Rachel Scalf and Madison Sundlof and Katelyn M Tessier and Daniel Peck and Matthew Ambrose and Cresta W Jones},
journal = {Echocardiography (Mount Kisco, N.Y.)},
year = {2026},
month = oct,
doi = {10.1111/echo.70655},
url = {https://europepmc.org/article/MED/42921837},
note = {CC BY},
}
RIS
TY - JOUR
TI - Fetal Echocardiography After a Normal Anatomy Assessment: A Retrospective Cohort of In Vitro Fertilization Pregnancies.
AU - Brianna Dickson
AU - Hannah Maher
AU - Savannah Maynard
AU - Rachel Scalf
AU - Madison Sundlof
AU - Katelyn M Tessier
AU - Daniel Peck
AU - Matthew Ambrose
AU - Cresta W Jones
PY - 2026
DA - 2026/10/01
JO - Echocardiography (Mount Kisco, N.Y.)
DO - 10.1111/echo.70655
UR - https://europepmc.org/article/MED/42921837
AB - Purpose To investigate the detection rate of congenital heart disease (CHD) on fetal echocardiogram after a normal and complete detailed fetal ultrasound among pregnancies conceived by in vitro fertilization (IVF).Methods This retrospective cohort study examined singleton IVF pregnancies that underwent a detailed fetal anatomic survey without any identified abnormalities, followed by fetal echocardiogram. The primary outcome was the rate of CHD diagnosis after normal and complete anatomic ultrasound. Patients with multifetal gestation, pre-gestational diabetes, a known family history of CHD, fetal abnormalities on anatomy ultrasound, or patients who had an incomplete initial anatomy ultrasound were excluded. Prenatal CHD was confirmed with neonatal imaging and infants were followed after birth.Results 300 pregnancies were included, and of these 266 had a normal and complete anatomy ultrasound. 1.5% (n = 4) of pregnancies had minor CHD identified on fetal echocardiography which was not identified on the anatomy ultrasound. None of the infants required cardiac-related interventions in the first year of life.Conclusion No major CHD was identified at fetal echocardiography after a normal and complete anatomic survey. Our results support the American Institute of Ultrasound in Medicine guidelines that state a dedicated fetal echocardiogram may be considered, but is not recommended, for singleton IVF pregnancies.
SN - 0742-2822
SN - 1540-8175
ER -