Skip to content
DraconiticResearch
Search Sources API
220,430 studies31 sourcesUpdated 38 min ago
Peer-reviewedCC BY-NC 4.0Archivos Peruanos de Cardiología y Cirugía Cardiovascular

Chronic Chagas Cardiomyopathy at a Peruvian National Referral Hospital: A Case Series

  • Karen Alejandra Serrano Carmen1
  • Diego Davila-Flores2
  • Paola Gisella Oliver Rengifo3
  1. 1Universidad Peruana Cayetano Heredia, Lima, Peru. Universidad Peruana Cayetano Heredia Universidad Peruana Cayetano Heredia Lima Peru
  2. 2Instituto Nacional Cardiovascular, INCOR-EsSalud, Lima, Peru Instituto Nacional Cardiovascular INCOR-EsSalud Lima Peru
  3. 3Hospital Nacional Arzobispo Loayza, Lima, Peru Hospital Nacional Arzobispo Loayza Lima Peru
Read full textPDFDOICite

Abstract

Objectives:: To describe the cardiovascular manifestations and clinical course of patients with chronic Chagas cardiomyopathy at a Peruvian national hospital.

Materials and methods: : Descriptive retrospective case series (2021-2025). Nine patients with serologically confirmed Trypanosoma cruzi infection were assessed by electrocardiography, echocardiography, and/or 24-hour Holter monitoring; a predominant cardiovascular phenotype was assigned to each.

Results: : The mean age was 50.1 ± 6.8 years; 55.6% were male, and 66.7% came from the Peruvian Amazon. The heart failure phenotype predominated (55.6%), with ejection fractions of 15-39%, followed by ventricular arrhythmias (22.2%) and conduction disorders (22.2%). Two patients (22.2%) received permanent pacemakers, one (11.1%) received an implantable cardioverter-defibrillator, and two (22.2%) died.

Conclusions: : The three classic phenotypes coexisted, with advanced disease at diagnosis. Chagas disease should be considered cases of nonischemic dilated cardiomyopathy or conduction disorders.

Related

  1. Facilitators and barriers to nurses’ adherence to traumatic brain injury management guidelines at the accident and emergency unit in a national referral hospital in Uganda: a qualitative study
    Peter Nyakuni, Aloysius Gonzaga Mubuuke, Jonathan Izudi +3
    BMJ OpenPeer-reviewedLicence not statedGeneral medicineCrossref
  2. The Lived Experiences of Long-Term Users of Copper-T Intrauterine Devices: A phenomenological Qualitative Study among women at Kawempe National Referral Hospital in Uganda
    I. S. pious, J. Beyeza-Kashesya, I. Namagembe +9
    medRxivPreprintAll rights reservedFull textObstetrics, gynaecology & paediatricsmedRxiv
  3. Burden and temporal trends of cardiovascular disease among medical inpatients and age-specific and sex-specific risk of CVD-related hospitalisation at a national referral hospital in Uganda: a retrospective cohort study
    Christopher Odong, Charles Musoke, Levi Kwarisima +16
    BMJ OpenPeer-reviewedLicence not statedGeneral medicineCrossref
  4. Health-related quality of life in pediatric patients with stage 5 chronic kidney disease receiving kidney replacement therapy in Honduras: a descriptive cross-sectional study from a national referral center
    Carlos Solórzano Flores, Kelvin Medina, Alejandra Galindo +2
    Childhood kidney diseasesPeer-reviewedCC BY-NCFull textGeneral medicineEurope PMC
  5. Clinical and molecular profile of Klebsiella pneumoniae bloodstream infections in a national referral hospital in the Philippines
    Christian Francisco, Angelo dela Tonga, Stessi Marie Geganzo +9
    IJID RegionsPeer-reviewedCC BY 4.0Full textInfectious diseasePMC

Cite

BibTeXRIS
BibTeX
@article{carmen2026chronic,
  title = {{Chronic Chagas Cardiomyopathy at a Peruvian National Referral Hospital: A Case Series}},
  author = {Karen Alejandra Serrano Carmen and Diego Davila-Flores and Paola Gisella Oliver Rengifo},
  journal = {Archivos Peruanos de Cardiología y Cirugía Cardiovascular},
  year = {2026},
  month = sep,
  doi = {10.47487/apcyccv.v7i3.651},
  url = {https://doi.org/10.47487/apcyccv.v7i3.651},
  note = {CC BY-NC 4.0},
}
RIS
TY  - JOUR
TI  - Chronic Chagas Cardiomyopathy at a Peruvian National Referral Hospital: A Case Series
AU  - Karen Alejandra Serrano Carmen
AU  - Diego Davila-Flores
AU  - Paola Gisella Oliver Rengifo
PY  - 2026
DA  - 2026/09/26
JO  - Archivos Peruanos de Cardiología y Cirugía Cardiovascular
DO  - 10.47487/apcyccv.v7i3.651
UR  - https://doi.org/10.47487/apcyccv.v7i3.651
AB  - Objectives:: To describe the cardiovascular manifestations and clinical course of patients with chronic Chagas cardiomyopathy at a Peruvian national hospital.  Materials and methods: : Descriptive retrospective case series (2021-2025). Nine patients with serologically confirmed Trypanosoma cruzi infection were assessed by electrocardiography, echocardiography, and/or 24-hour Holter monitoring; a predominant cardiovascular phenotype was assigned to each.  Results: : The mean age was 50.1 ± 6.8 years; 55.6% were male, and 66.7% came from the Peruvian Amazon. The heart failure phenotype predominated (55.6%), with ejection fractions of 15-39%, followed by ventricular arrhythmias (22.2%) and conduction disorders (22.2%). Two patients (22.2%) received permanent pacemakers, one (11.1%) received an implantable cardioverter-defibrillator, and two (22.2%) died.  Conclusions: : The three classic phenotypes coexisted, with advanced disease at diagnosis. Chagas disease should be considered cases of nonischemic dilated cardiomyopathy or conduction disorders.
SN  - 2708-7212
ER  -