Cognitive Control Neural Correlates of Negative Affective in Psychosis Spectrum Disorders: A Laboratory and Ecological Momentary Assessment Study
Abstract
Individuals with schizophrenia-spectrum (SZ) and bipolar-spectrum disorders (BD) report experiencing heightened negative affect (NA), which can be operationalized as stable traits and dynamic states. While cognitive control is a potential underlying mechanism, identifying neural underpinning of NA has been challenging. This could be due to the lack of such investigation, but also a comprehensive framework to investigate the association specificity. Data were collected from 105 participants (34 SZ, 34 BD, 37 healthy control [HC]) on the five-factor model of personality traits, cognitive control electroencephalography (EEG), and self-reported mood and contexts via ecological momentary assessment (EMA). Cognitive control indices of EEG were extracted as event-related potentials (ERPs) and time-frequency theta-band activities from three flanker tasks varying in valence (neutral, unpleasant, and pleasant). Participants with SZ and BD generally reported higher NA traits, lower Extraversion, lower Conscientiousness traits, higher Psychoticism, and high average and fluctuation in EMA NA-related experiences than HC participants. Participants with SZ experienced more EMA unpleasant events, were more upset by them, and put more effort into avoiding them. EEG theta-band power from the arrow task was associated mostly with NA-related traits and tendency, and theta-band power from the unpleasant task was associated with EMA unpleasant event occurrence and reactions. ERPs and theta phase activities did not relate to any traits or daily experiences, and no other traits and experiences were related to EEG measures. Cognitive control EEG theta-band power was associated with trait and state NA specifically, potentially reflecting a transdiagnostic indicator of cognitive control and neural mechanism underlying stress-vulnerability in SZ and BD.
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BibTeX
@misc{suzuki2026cognitive,
title = {{Cognitive Control Neural Correlates of Negative Affective in Psychosis Spectrum Disorders: A Laboratory and Ecological Momentary Assessment Study}},
author = {Takakuni Suzuki and Margo W. Menkes and Maureen Walton and Melvin G McInnis and Jian Kang and Tara A. Niendam and Ivy Fei Tso and Stephan F. Taylor},
howpublished = {PsyArXiv},
year = {2026},
month = sep,
doi = {10.31234/osf.io/f7yzs_v1},
url = {https://osf.io/preprints/psyarxiv/f7yzs_v1/},
note = {CC BY 4.0},
}
RIS
TY - UNPB
TI - Cognitive Control Neural Correlates of Negative Affective in Psychosis Spectrum Disorders: A Laboratory and Ecological Momentary Assessment Study
AU - Takakuni Suzuki
AU - Margo W. Menkes
AU - Maureen Walton
AU - Melvin G McInnis
AU - Jian Kang
AU - Tara A. Niendam
AU - Ivy Fei Tso
AU - Stephan F. Taylor
PY - 2026
DA - 2026/09/21
PB - PsyArXiv
DO - 10.31234/osf.io/f7yzs_v1
UR - https://osf.io/preprints/psyarxiv/f7yzs_v1/
AB - Individuals with schizophrenia-spectrum (SZ) and bipolar-spectrum disorders (BD) report experiencing heightened negative affect (NA), which can be operationalized as stable traits and dynamic states. While cognitive control is a potential underlying mechanism, identifying neural underpinning of NA has been challenging. This could be due to the lack of such investigation, but also a comprehensive framework to investigate the association specificity. Data were collected from 105 participants (34 SZ, 34 BD, 37 healthy control [HC]) on the five-factor model of personality traits, cognitive control electroencephalography (EEG), and self-reported mood and contexts via ecological momentary assessment (EMA). Cognitive control indices of EEG were extracted as event-related potentials (ERPs) and time-frequency theta-band activities from three flanker tasks varying in valence (neutral, unpleasant, and pleasant). Participants with SZ and BD generally reported higher NA traits, lower Extraversion, lower Conscientiousness traits, higher Psychoticism, and high average and fluctuation in EMA NA-related experiences than HC participants. Participants with SZ experienced more EMA unpleasant events, were more upset by them, and put more effort into avoiding them. EEG theta-band power from the arrow task was associated mostly with NA-related traits and tendency, and theta-band power from the unpleasant task was associated with EMA unpleasant event occurrence and reactions. ERPs and theta phase activities did not relate to any traits or daily experiences, and no other traits and experiences were related to EEG measures. Cognitive control EEG theta-band power was associated with trait and state NA specifically, potentially reflecting a transdiagnostic indicator of cognitive control and neural mechanism underlying stress-vulnerability in SZ and BD.
ER -