Choroidal thickness postural changes in healthy young adults
4 affiliations
- 1Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno
- 2Eye Unit, Maria SS Addolorata Hospital, ASL Salerno
- 3Eye Unit, San Leonardo Hospital, ASL NA 3
- 4Eye Unit, Pellegrini Hospital, ASL Napoli 1
Abstract
The purpose of this study was to evaluate choroidal thickness (ChT) postural changes between sitting and standing position in healthy young adults. 100 patients, 56 males and 44 females (mean age 26,8 ± 2 years) underwent a complete eye examination, including ChT, axial length (AL) and IOP measurements. ChT measurement was performed in sitting and standing positions. In OD, mean subfoveal ChT was 279 μm ± 96 μm in sitting position and 267 μm ± 94 μm in standing position (p < 0.001); mean nasal ChT was 224 μm ± 88 μm in sitting position and 214 μm ± 88 μm in standing position (p < 0.001); mean temporal ChT was 287 ± 84 μm in sitting position and 275 μm ± 82 μm in standing position (p < 0.001). We demonstrated that, when subjects change their position from sitting to standing, a thinning in ChT is detected. The physiology behind the described variations is still incompletely understood and may be tied to the activation of the baroreceptor reflex caused by postural changes. More studies should be performed to prove the usefulness of ChT variation as a biomarker in autonomic nervous system (ANS) diseases, such as Multiple system atrophy (MSA) and Parkinson’s disease (PD).
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BibTeX
@article{bernardo2026choroidal,
title = {{Choroidal thickness postural changes in healthy young adults}},
author = {Maddalena De Bernardo and Marco Gioia and Andrea Valerio Marino and Martina De Luca and Nicola Rosa},
journal = {Scientific Reports},
year = {2026},
month = jul,
doi = {10.1038/s41598-026-62457-8},
url = {https://doi.org/10.1038/s41598-026-62457-8},
note = {CC BY},
}
RIS
TY - JOUR
TI - Choroidal thickness postural changes in healthy young adults
AU - Maddalena De Bernardo
AU - Marco Gioia
AU - Andrea Valerio Marino
AU - Martina De Luca
AU - Nicola Rosa
PY - 2026
DA - 2026/07/01
JO - Scientific Reports
DO - 10.1038/s41598-026-62457-8
UR - https://doi.org/10.1038/s41598-026-62457-8
AB - The purpose of this study was to evaluate choroidal thickness (ChT) postural changes between sitting and standing position in healthy young adults. 100 patients, 56 males and 44 females (mean age 26,8 ± 2 years) underwent a complete eye examination, including ChT, axial length (AL) and IOP measurements. ChT measurement was performed in sitting and standing positions. In OD, mean subfoveal ChT was 279 μm ± 96 μm in sitting position and 267 μm ± 94 μm in standing position (p < 0.001); mean nasal ChT was 224 μm ± 88 μm in sitting position and 214 μm ± 88 μm in standing position (p < 0.001); mean temporal ChT was 287 ± 84 μm in sitting position and 275 μm ± 82 μm in standing position (p < 0.001). We demonstrated that, when subjects change their position from sitting to standing, a thinning in ChT is detected. The physiology behind the described variations is still incompletely understood and may be tied to the activation of the baroreceptor reflex caused by postural changes. More studies should be performed to prove the usefulness of ChT variation as a biomarker in autonomic nervous system (ANS) diseases, such as Multiple system atrophy (MSA) and Parkinson’s disease (PD).
SN - 2045-2322
ER -