Skip to content
DraconiticResearch
Search Sources API
197,788 studies31 sourcesUpdated 50 min ago
Peer-reviewedCC BYCureus

The Current State of Digital Variance Angiography: A Literature Review.

  1. 1Department of Foundational Sciences, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.

Abstract

Digital variance angiography (DVA), also referred to as kinetic imaging angiography, is an imaging technique that enhances vascular visualization by analyzing contrast flow motion. Although digital subtraction angiography (DSA) remains the current standard of care, DVA has demonstrated potential improvements in image quality and reductions in both radiation exposure and contrast use. This literature review aimed to evaluate currently available literature focusing on the use of DVA during angiographic procedures. The review was conducted using PubMed, EMBASE, and Web of Science, with the process being reflected in a Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) flowchart. Across multiple clinical applications, DVA consistently demonstrated higher objective image quality metrics including contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) as compared with DSA. Several studies reported that expert reviewers observed improved subjective image quality and substantial reductions in radiation exposure. In addition, DVA has also been shown to facilitate reduced use of contrast, potentially decreasing contrast-related complications and healthcare costs. Collectively, current evidence suggests that DVA represents a promising advancement in angiographic imaging, with the potential to deliver superior image quality with reduced radiation exposure and contrast use.

Related

  1. Single-Stage Computed Tomography Angiography, Percutaneous Coronary Intervention, and Transcatheter Aortic Valve Replacement in an Octogenarian With Femoral Neck Fracture, Non-ST-Elevation Myocardial Infarction, and Severe Aortic Stenosis: A Case Report and Literature Review of Multidisciplinary Approaches
    Ming Zhang, Xietian Pan, Lina Yang +9
    Reviews in cardiovascular medicinePeer-reviewedCC BYFull textCardiovascular medicineEurope PMC
  2. Osteoporosis: current diagnostic possibilities, a literature review
    Michał Swoboda, Wojciech Pluskiewicz
    Przeglad menopauzalny = Menopause reviewPeer-reviewedCC BY-NC-SAFull textGeneral medicineEurope PMC
  3. Pregnancy testing prior to iodine-131 thyroid therapy: a literature review of current recommendations
    Stephen J. Sozio, David Cohen, William Y. Raynor +1
    EJNMMI reportsPeer-reviewedCC BY-NC-NDFull textMedical imaging & radiologyEurope PMC
  4. Current Evidence, Diagnostic Challenges, and Contemporary Management of Lymphocytic Colitis: A Case Report and Literature Review
    Oziegbe Egbo, Ojevwe H Egbo, Faith I Omoregie +1
    CureusPeer-reviewedCC BYFull textGeneral medicineEurope PMC
  5. Current applications of transauricular vagus nerve stimulation in orthopedics: a narrative review of the literature
    Petros Kitsis, Thea Zisimou, Egor Kostin +3
    Annals of medicine and surgery (2012)Peer-reviewedCC BY-NC-NDFull textGeneral medicineEurope PMC
BibTeX
@article{scott2026current,
  title = {{The Current State of Digital Variance Angiography: A Literature Review.}},
  author = {Sierra Scott and Jonathan Platosz and Shannon N Smith and Sydney Elness and Suzanne I Riskin},
  journal = {Cureus},
  year = {2026},
  month = sep,
  doi = {10.7759/cureus.116912},
  url = {https://europepmc.org/article/MED/42928884},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - The Current State of Digital Variance Angiography: A Literature Review.
AU  - Sierra Scott
AU  - Jonathan Platosz
AU  - Shannon N Smith
AU  - Sydney Elness
AU  - Suzanne I Riskin
PY  - 2026
DA  - 2026/09/25
JO  - Cureus
DO  - 10.7759/cureus.116912
UR  - https://europepmc.org/article/MED/42928884
AB  - Digital variance angiography (DVA), also referred to as kinetic imaging angiography, is an imaging technique that enhances vascular visualization by analyzing contrast flow motion. Although digital subtraction angiography (DSA) remains the current standard of care, DVA has demonstrated potential improvements in image quality and reductions in both radiation exposure and contrast use. This literature review aimed to evaluate currently available literature focusing on the use of DVA during angiographic procedures. The review was conducted using PubMed, EMBASE, and Web of Science, with the process being reflected in a Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) flowchart. Across multiple clinical applications, DVA consistently demonstrated higher objective image quality metrics including contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) as compared with DSA. Several studies reported that expert reviewers observed improved subjective image quality and substantial reductions in radiation exposure. In addition, DVA has also been shown to facilitate reduced use of contrast, potentially decreasing contrast-related complications and healthcare costs. Collectively, current evidence suggests that DVA represents a promising advancement in angiographic imaging, with the potential to deliver superior image quality with reduced radiation exposure and contrast use.
SN  - 2168-8184
ER  -