Skin Graft With Amniotic Membrane: Case Report of the Sandwich Technique in a Burn Hand.
5 affiliations
- 1From the Department of Plastic and Reconstructive Surgery, Hospital Simón Bolivar, Bogotá, Colombia.
- 2Department of Plastic and Reconstructive Surgery, Los Cobos Medical Center, Bogotá, Colombia.
- 3Universidad El Bosque Plastic and Reconstructive Surgery Research Group, Bogotá, Colombia.
- 4Universidad El Bosque, Bogotá, Colombia.
- 5Universidad Autonoma de Bucaramanga, Bucaramanga, Colombia.
Abstract
Deep burns of the hand represent a major reconstructive challenge due to the critical functional role of the hand and the high risk of long-term disabling sequelae. The "sandwich" technique, combining an autologous skin graft with an amniotic membrane, has been described as a biological dressing with potential anti-inflammatory and wound-healing properties. A 32-year-old woman presented with a full-thickness burn involving the right palm and wrist after contact with an industrial thermal press. Following eschar excision, a full-thickness skin graft was harvested from the inner region of the ipsilateral arm; the donor site was closed primarily by advancing the wound edges with absorbable monofilament intradermal sutures and covered with Micropore tape to reduce tension. Because of incomplete well-vascularized perfusion of the recipient bed and the risk of functional impairment, an amniotic membrane was placed as an additional protective layer over the graft. By the seventh postoperative day, the graft showed satisfactory take, with no evidence of infection. At 12 months of follow-up, complete integration was achieved, with preserved joint mobility and a favorable aesthetic outcome. This case illustrates the technical feasibility of using preserved amniotic membrane as an overlay biological dressing over a full-thickness skin graft in a functionally critical palmar burn. Although satisfactory healing was observed, no causal conclusion can be drawn regarding improved graft integration, scar modulation, or functional preservation based on a single case. Further comparative studies are needed to determine whether the benefits reported in other grafting contexts also apply to full-thickness skin grafting.
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BibTeX
@article{cordoba2026skin,
title = {{Skin Graft With Amniotic Membrane: Case Report of the Sandwich Technique in a Burn Hand.}},
author = {Natalia Santamaria Cordoba and Adriana Parra Gomez and Sebastian Murcia Espino and Mauricio Alfonso Uribe Rodríguez and Maria Paula Mendez Gaitan},
journal = {Plastic and reconstructive surgery. Global open},
year = {2026},
month = oct,
doi = {10.1097/gox.0000000000008218},
url = {https://europepmc.org/article/MED/42903501},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Skin Graft With Amniotic Membrane: Case Report of the Sandwich Technique in a Burn Hand.
AU - Natalia Santamaria Cordoba
AU - Adriana Parra Gomez
AU - Sebastian Murcia Espino
AU - Mauricio Alfonso Uribe Rodríguez
AU - Maria Paula Mendez Gaitan
PY - 2026
DA - 2026/10/19
JO - Plastic and reconstructive surgery. Global open
DO - 10.1097/gox.0000000000008218
UR - https://europepmc.org/article/MED/42903501
AB - Deep burns of the hand represent a major reconstructive challenge due to the critical functional role of the hand and the high risk of long-term disabling sequelae. The "sandwich" technique, combining an autologous skin graft with an amniotic membrane, has been described as a biological dressing with potential anti-inflammatory and wound-healing properties. A 32-year-old woman presented with a full-thickness burn involving the right palm and wrist after contact with an industrial thermal press. Following eschar excision, a full-thickness skin graft was harvested from the inner region of the ipsilateral arm; the donor site was closed primarily by advancing the wound edges with absorbable monofilament intradermal sutures and covered with Micropore tape to reduce tension. Because of incomplete well-vascularized perfusion of the recipient bed and the risk of functional impairment, an amniotic membrane was placed as an additional protective layer over the graft. By the seventh postoperative day, the graft showed satisfactory take, with no evidence of infection. At 12 months of follow-up, complete integration was achieved, with preserved joint mobility and a favorable aesthetic outcome. This case illustrates the technical feasibility of using preserved amniotic membrane as an overlay biological dressing over a full-thickness skin graft in a functionally critical palmar burn. Although satisfactory healing was observed, no causal conclusion can be drawn regarding improved graft integration, scar modulation, or functional preservation based on a single case. Further comparative studies are needed to determine whether the benefits reported in other grafting contexts also apply to full-thickness skin grafting.
SN - 2169-7574
ER -