Comparative analysis of bioenergetic pathways in Medusozoa based on integrated genomic, transcriptomic and proteomic data.
- 1Department of Biological Sciences, University of Texas at El Paso, El Paso, TX, United States.
- 2Laboratory of Bioenergetics and Molecular Genomics, Centro de Investigacion en Alimentacion y Desarrollo, A.C. (CIAD), Hermosillo, Sonora, Mexico.
Abstract
Introduction
Jellyfish possess the biochemical and physiological capabilities that enable them to survive from the beginning of the animal era to the impacts of global warming (ocean warming and deoxygenation) on the seas today. Despite their confirmed ability to bloom, significant gaps remain about the molecular basis of specific physiological responses, and limited data allow us to understand the metabolic pathways that enable medusozoans to transform energy and successfully cope with the challenges the marine environment imposes.Methods
This research integrates and describes prior knowledge (genomic and transcriptomic information) and experimental data (a mitochondrial proteome) to compare, analyze, and reconstruct the major bioenergetic pathways of Medusozoa.Results
From the conserved glycolytic enzymes to the novel and distinctive molecules enabling jellyfish to build large energy reserves, this manuscript describes the presence of alternative enzymes composing the mitochondrial branched respiratory chain, anaerobic metabolism, and the phosphagen systems in the four classes of true jellyfish.Discussion
These results may contribute, from an energetic perspective, to explain the physiological ability of jellyfish to cope with environmental changes by increasing their populations and occupying new environments.
Related
- Integrated genomic, transcriptomic, and proteomic analyses prioritize cadmium-responsive class III peroxidases in Salix variegata
- Integrated Physiological, Transcriptomic, and Proteomic Analyses Reveal Alkali Stress Response and Tolerance Mechanisms of Rhododendron obtusum ‘Fenzhuanglou’ Seedlings
- Integrated transcriptomic and proteomic analyses of the mechanisms of Citrobacter freundii–induced ‘‘water bubble disease’’ in Macrobrachium rosenbergii
- iGEX: an interactive Gene EXpression exploration platform for the analysis of transcriptomic and proteomic datasets
- Transcriptomic and proteomic analysis of quiescent epimastigotes as a resource for investigating Trypanosoma cruzi persistence
BibTeX
@article{gameromora2026comparative,
title = {{Comparative analysis of bioenergetic pathways in Medusozoa based on integrated genomic, transcriptomic and proteomic data.}},
author = {Edgar Gamero-Mora and Legna Gabriela Pasos-Ramirez and Julio Cesar Barcelo-Navarro and Adriana Muhlia-Almazan},
journal = {Frontiers in physiology},
year = {2026},
month = oct,
doi = {10.3389/fphys.2026.1932200},
url = {https://europepmc.org/article/MED/42898912},
note = {CC BY},
}
RIS
TY - JOUR
TI - Comparative analysis of bioenergetic pathways in Medusozoa based on integrated genomic, transcriptomic and proteomic data.
AU - Edgar Gamero-Mora
AU - Legna Gabriela Pasos-Ramirez
AU - Julio Cesar Barcelo-Navarro
AU - Adriana Muhlia-Almazan
PY - 2026
DA - 2026/10/05
JO - Frontiers in physiology
DO - 10.3389/fphys.2026.1932200
UR - https://europepmc.org/article/MED/42898912
AB - Introduction Jellyfish possess the biochemical and physiological capabilities that enable them to survive from the beginning of the animal era to the impacts of global warming (ocean warming and deoxygenation) on the seas today. Despite their confirmed ability to bloom, significant gaps remain about the molecular basis of specific physiological responses, and limited data allow us to understand the metabolic pathways that enable medusozoans to transform energy and successfully cope with the challenges the marine environment imposes.Methods This research integrates and describes prior knowledge (genomic and transcriptomic information) and experimental data (a mitochondrial proteome) to compare, analyze, and reconstruct the major bioenergetic pathways of Medusozoa.Results From the conserved glycolytic enzymes to the novel and distinctive molecules enabling jellyfish to build large energy reserves, this manuscript describes the presence of alternative enzymes composing the mitochondrial branched respiratory chain, anaerobic metabolism, and the phosphagen systems in the four classes of true jellyfish.Discussion These results may contribute, from an energetic perspective, to explain the physiological ability of jellyfish to cope with environmental changes by increasing their populations and occupying new environments.
SN - 1664-042X
ER -