Global Trends and Research Hotspots of Interventions for Post-Stroke Cognitive Impairment: A Bibliometric Analysis from 2005 to 2025.
- 1Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
- 2Stroke Prevention and Translational Research Center, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
- 3National Stroke Administration Office, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Abstract
Background: Despite the growing clinical importance of post-stroke cognitive impairment (PSCI), standardized and effective interventions remain limited, and no comprehensive bibliometric analysis has systematically mapped global research trends in PSCI interventions. This study aimed to outline the global research landscape and identify emerging trends and future research directions. Methods: Publications regarding clinical interventions for PSCI were retrieved from the Web of Science Core Collection database from 1 January 2005 to 31 December 2025. Utilizing CiteSpace and VOSviewer software, this study conducted a comprehensive bibliometric analysis and visualization of the literature. The analysis encompassed research directions, publication trends, countries/regions, institutions, authors, source journals, and keyword characteristics. Results: After removing duplicates and applying strict inclusion criteria, 789 English-language articles and reviews were included. The overall findings indicated that annual publications on PSCI-related clinical interventions steadily increased, with rapid growth since 2015, reaching a peak of 130 publications in 2025. China produced the largest volume of publications (n = 358), with the USA acting as the core hub of international collaborative research. Chinese institutions dominated publication volume, but international institutions had greater research impact. The author network was large but lacked high-productivity core scholars, and cross-team collaboration remained limited. Highly cited studies mainly addressed cognitive assessment, pathological mechanisms, and clinical guidelines. Keyword analysis revealed that research hotspots have gradually shifted from functional evaluation to neural mechanism-based intervention research, and the standardization of outcome assessment has become a research focus. Conclusions: Global publications on PSCI interventions show a clear increasing trend, accelerating after 2015. Nevertheless, high-quality, multicenter randomized controlled trials are still insufficient. Future research should prioritize rigorously designed clinical trials to establish solid clinical evidence and formulate unified evaluation criteria for cognitive outcomes.
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BibTeX
@article{li2026global,
title = {{Global Trends and Research Hotspots of Interventions for Post-Stroke Cognitive Impairment: A Bibliometric Analysis from 2005 to 2025.}},
author = {Shaofei Li and Wei Sun and Benke Zhao and Aini He and Xuefan Yao and Houlin Lai and Kehui Ma and Jiaxin Gao and Jiayin Xiao and Luda Feng and Haiqing Song},
journal = {Healthcare (Basel, Switzerland)},
year = {2026},
month = sep,
doi = {10.3390/healthcare14193210},
url = {https://europepmc.org/article/MED/42881649},
note = {CC BY},
}
RIS
TY - JOUR
TI - Global Trends and Research Hotspots of Interventions for Post-Stroke Cognitive Impairment: A Bibliometric Analysis from 2005 to 2025.
AU - Shaofei Li
AU - Wei Sun
AU - Benke Zhao
AU - Aini He
AU - Xuefan Yao
AU - Houlin Lai
AU - Kehui Ma
AU - Jiaxin Gao
AU - Jiayin Xiao
AU - Luda Feng
AU - Haiqing Song
PY - 2026
DA - 2026/09/28
JO - Healthcare (Basel, Switzerland)
DO - 10.3390/healthcare14193210
UR - https://europepmc.org/article/MED/42881649
AB - Background: Despite the growing clinical importance of post-stroke cognitive impairment (PSCI), standardized and effective interventions remain limited, and no comprehensive bibliometric analysis has systematically mapped global research trends in PSCI interventions. This study aimed to outline the global research landscape and identify emerging trends and future research directions. Methods: Publications regarding clinical interventions for PSCI were retrieved from the Web of Science Core Collection database from 1 January 2005 to 31 December 2025. Utilizing CiteSpace and VOSviewer software, this study conducted a comprehensive bibliometric analysis and visualization of the literature. The analysis encompassed research directions, publication trends, countries/regions, institutions, authors, source journals, and keyword characteristics. Results: After removing duplicates and applying strict inclusion criteria, 789 English-language articles and reviews were included. The overall findings indicated that annual publications on PSCI-related clinical interventions steadily increased, with rapid growth since 2015, reaching a peak of 130 publications in 2025. China produced the largest volume of publications (n = 358), with the USA acting as the core hub of international collaborative research. Chinese institutions dominated publication volume, but international institutions had greater research impact. The author network was large but lacked high-productivity core scholars, and cross-team collaboration remained limited. Highly cited studies mainly addressed cognitive assessment, pathological mechanisms, and clinical guidelines. Keyword analysis revealed that research hotspots have gradually shifted from functional evaluation to neural mechanism-based intervention research, and the standardization of outcome assessment has become a research focus. Conclusions: Global publications on PSCI interventions show a clear increasing trend, accelerating after 2015. Nevertheless, high-quality, multicenter randomized controlled trials are still insufficient. Future research should prioritize rigorously designed clinical trials to establish solid clinical evidence and formulate unified evaluation criteria for cognitive outcomes.
SN - 2227-9032
ER -