Peer-reviewedLicence not statedScience Advances6 Nov 2026

Reciprocal control of genome instability and RNA processing in cancer: Mechanisms and therapeutic opportunities

Mariachiara Grieco^1,2
Federica Giugliano^1,2,3
Ernesto Guccione⁴
Ilio Vitale^2,5
Matteo Cereda^1,2,6

6 affiliations

¹Department of Oncology and Hemato-Oncology, University of Milan, 20142 Milan, Italy.
²Italian Institute for Genomic Medicine, c/o IRCCS, Str. Prov.le 142, km 3.95, 10060 Candiolo (TO), Italy.
³Department of Medical Oncology, Gustave Roussy, Villejuif, France.
⁴Center for OncoGenomics and Innovative Therapeutics (COGIT), Department of Oncological Sciences and Pharmacological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
⁵Istituto Nazionale Oncologico Candiolo (INOC), IRCCS, Candiolo (TO), Italy.
⁶IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.

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BibTeX

@article{grieco2026reciprocal,
  title = {{Reciprocal control of genome instability and RNA processing in cancer: Mechanisms and therapeutic opportunities}},
  author = {Mariachiara Grieco and Federica Giugliano and Ernesto Guccione and Ilio Vitale and Matteo Cereda},
  journal = {Science Advances},
  year = {2026},
  month = nov,
  doi = {10.1126/sciadv.aei7541},
  url = {https://www.science.org/doi/abs/10.1126/sciadv.aei7541},
}

RIS

TY  - JOUR
TI  - Reciprocal control of genome instability and RNA processing in cancer: Mechanisms and therapeutic opportunities
AU  - Mariachiara Grieco
AU  - Federica Giugliano
AU  - Ernesto Guccione
AU  - Ilio Vitale
AU  - Matteo Cereda
PY  - 2026
DA  - 2026/11/06
JO  - Science Advances
DO  - 10.1126/sciadv.aei7541
UR  - https://www.science.org/doi/abs/10.1126/sciadv.aei7541
SN  - 2375-2548
ER  -

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