Percutaneous Coronary Interventions: Current Innovations and Future Perspectives
- 1Cardiology Department, Lausanne University Hospital and University of Lausanne, 1005 Lausanne, Switzerland
- 2Cardiology Department, Clinique Pasteur, 31300 Toulouse, France
Abstract
Percutaneous coronary intervention (PCI) has undergone remarkable evolution over the past decades, leading to substantial improvements in procedural success, patient outcomes, and long-term prognosis, although significant challenges remain. Recent technological and therapeutic advances are reshaping contemporary PCI practice. In acute coronary syndromes, novel thrombectomy approaches and emerging reperfusion strategies aim to improve myocardial salvage. In chronic coronary syndromes, the increasing adoption of intracoronary imaging, advanced calcium modification technologies, drug-coated balloons, and next-generation bioresorbable scaffolds is driving the transition toward more individualized and less implant-dependent revascularization strategies. Parallel developments in antithrombotic therapy, including shortened dual antiplatelet therapy (DAPT) regimens, aspirin-free approaches, and personalized treatment algorithms, seek to improve the balance between ischemic protection and bleeding risk. Furthermore, growing recognition of coronary microvascular disease has expanded the focus of PCI beyond epicardial stenoses, highlighting the importance of functional assessment and targeted therapeutic strategies. Finally, artificial intelligence (AI) is emerging as a transformative tool with potential applications in procedural planning, imaging interpretation, physiological assessment, and clinical decision-making. This review summarizes the most relevant contemporary innovations in PCI and discusses future perspectives that are likely to redefine the management of coronary artery disease.
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BibTeX
@article{liabot2026percutaneous,
title = {{Percutaneous Coronary Interventions: Current Innovations and Future Perspectives}},
author = {Quentin Liabot and Aurelia Zimmerli and Benjamin Honton and Adil Salihu and Olivier Muller and Stephane Fournier and David Meier},
journal = {Journal of Clinical Medicine},
year = {2026},
month = nov,
doi = {10.3390/jcm15218506},
url = {https://www.mdpi.com/2077-0383/15/21/8506},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Percutaneous Coronary Interventions: Current Innovations and Future Perspectives
AU - Quentin Liabot
AU - Aurelia Zimmerli
AU - Benjamin Honton
AU - Adil Salihu
AU - Olivier Muller
AU - Stephane Fournier
AU - David Meier
PY - 2026
DA - 2026/11/02
JO - Journal of Clinical Medicine
DO - 10.3390/jcm15218506
UR - https://www.mdpi.com/2077-0383/15/21/8506
AB - Percutaneous coronary intervention (PCI) has undergone remarkable evolution over the past decades, leading to substantial improvements in procedural success, patient outcomes, and long-term prognosis, although significant challenges remain. Recent technological and therapeutic advances are reshaping contemporary PCI practice. In acute coronary syndromes, novel thrombectomy approaches and emerging reperfusion strategies aim to improve myocardial salvage. In chronic coronary syndromes, the increasing adoption of intracoronary imaging, advanced calcium modification technologies, drug-coated balloons, and next-generation bioresorbable scaffolds is driving the transition toward more individualized and less implant-dependent revascularization strategies. Parallel developments in antithrombotic therapy, including shortened dual antiplatelet therapy (DAPT) regimens, aspirin-free approaches, and personalized treatment algorithms, seek to improve the balance between ischemic protection and bleeding risk. Furthermore, growing recognition of coronary microvascular disease has expanded the focus of PCI beyond epicardial stenoses, highlighting the importance of functional assessment and targeted therapeutic strategies. Finally, artificial intelligence (AI) is emerging as a transformative tool with potential applications in procedural planning, imaging interpretation, physiological assessment, and clinical decision-making. This review summarizes the most relevant contemporary innovations in PCI and discusses future perspectives that are likely to redefine the management of coronary artery disease.
SN - 2077-0383
ER -