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Peer-reviewedCC BY 4.0Contact Dermatitis

Recreational Allergic Contact Dermatitis to “Epoxy UV ” Resins: A New Source of Exposure to Hidden (Meth)acrylates

Abstract

Background Several cases of contact allergy to epoxy resins used in creative hobbies have been reported in recent years but not to “epoxy UV” resins. Objectives To determine which components present in “epoxy UV” resins were responsible for allergic contact dermatitis in three patients who used them to make jewellery as a creative hobby and to describe the clinical and chemical analytical work‐up. Methods The three patients with eczematous skin eruptions from “epoxy UV” resin were patch tested with a baseline series and epoxy series and/or additional (meth)acrylates, and in some cases with different benzophenones (patch tests and photo‐patch tests). Proton Nuclear Magnetic Resonance (NMR) of three of the resins used was performed in order to determine their composition. Results All patients were shown to be sensitised to (meth)acrylates but not epoxy. Proton NMR could identify 2‐hydroxyethyl methacrylate (2‐HEMA) and an ethoxylated bisphenol A‐based diacrylate oligomer in the three tested resins. For two resins, di(ethylene glycol) diacrylate and poly(propylene glycol) diacrylate were also detected. The resin of one patient could not be analysed because of a technical problem. Conclusion Incorrectly labelled “epoxy UV” resins used in recreational activities are a new hidden source of sensitization to (meth)acrylates, not to epoxy compounds tested.

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BibTeX
@article{raisonpeyron2026recreational,
  title = {{Recreational Allergic Contact Dermatitis to “Epoxy UV ” Resins: A New Source of Exposure to Hidden (Meth)acrylates}},
  author = {Nadia Raison‐peyron and Sylvain Caillol and Jean Luc Bourrain and Eva Ibeka and Claire Negrell},
  journal = {Contact Dermatitis},
  year = {2026},
  month = oct,
  doi = {10.1111/cod.70225},
  url = {https://hal.science/hal-05793853v1},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Recreational Allergic Contact Dermatitis to “Epoxy UV ” Resins: A New Source of Exposure to Hidden (Meth)acrylates
AU  - Nadia Raison‐peyron
AU  - Sylvain Caillol
AU  - Jean Luc Bourrain
AU  - Eva Ibeka
AU  - Claire Negrell
PY  - 2026
DA  - 2026/10/12
JO  - Contact Dermatitis
DO  - 10.1111/cod.70225
UR  - https://hal.science/hal-05793853v1
AB  - Background Several cases of contact allergy to epoxy resins used in creative hobbies have been reported in recent years but not to “epoxy UV” resins. Objectives To determine which components present in “epoxy UV” resins were responsible for allergic contact dermatitis in three patients who used them to make jewellery as a creative hobby and to describe the clinical and chemical analytical work‐up. Methods The three patients with eczematous skin eruptions from “epoxy UV” resin were patch tested with a baseline series and epoxy series and/or additional (meth)acrylates, and in some cases with different benzophenones (patch tests and photo‐patch tests). Proton Nuclear Magnetic Resonance (NMR) of three of the resins used was performed in order to determine their composition. Results All patients were shown to be sensitised to (meth)acrylates but not epoxy. Proton NMR could identify 2‐hydroxyethyl methacrylate (2‐HEMA) and an ethoxylated bisphenol A‐based diacrylate oligomer in the three tested resins. For two resins, di(ethylene glycol) diacrylate and poly(propylene glycol) diacrylate were also detected. The resin of one patient could not be analysed because of a technical problem. Conclusion Incorrectly labelled “epoxy UV” resins used in recreational activities are a new hidden source of sensitization to (meth)acrylates, not to epoxy compounds tested.
SN  - 0105-1873
SN  - 1600-0536
ER  -