Echocardiographic Parameters in the Assessment of Tricuspid Regurgitation Prognosis: What Is New?
- 1Department of Cardiology, Vall d’Hebron Hospital Universitari, Vall d’Hebron Barcelona Hospital Campus, 08035 Barcelona, Spain
- 2Cardiovascular Diseases, Vall d′Hebron Institut de Recerca (VHIR), Vall d’Hebron Hospital Universitari, Vall d’Hebron Barcelona Hospital Campus, Passeig Vall d’Hebron 119-129, 08035 Barcelona, Spain
Abstract
Tricuspid regurgitation (TR) is associated with adverse clinical outcomes, highlighting the need for echocardiographic assessment beyond conventional severity grading. This narrative review examines the prognostic value and clinical applicability of established and emerging echocardiographic parameters. TR phenotype influences prognosis and response to transcatheter intervention, with more favourable outcomes in atrial than ventricular functional TR. The five-grade TR classification improves risk stratification, with massive or torrential TR associated with worse outcomes despite comparable procedural success. Right ventricular–pulmonary arterial coupling provides valuable prognostic information and may help identify an optimal therapeutic window for transcatheter intervention, particularly in patients with intermediate coupling values. The GLIDE score helps predict anatomical suitability and procedural success for transcatheter edge-to-edge repair, whereas high TRI-SCORE values (≥6) identify patients in whom a significant survival benefit from repair has not been demonstrated. Treatment decisions should therefore integrate symptoms, overall clinical status, procedural feasibility, and expected benefit through individualized Heart Team assessment. Following intervention, the severity of residual TR, ideally mild or less, remains a key determinant of procedural success.
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BibTeX
@article{rocca2026echocardiographic,
title = {{Echocardiographic Parameters in the Assessment of Tricuspid Regurgitation Prognosis: What Is New?}},
author = {Bianca Rocca and Javier Solsona-Caravaca and Martin Roncaglia and Nuria Vallejo and Víctor González Fernández and Pablo E. Tobías-Castillo and Gisela Teixidó-Tura and Ruper Oliveró-Soldevila and Guillem Casas and Filipa Valente and Oro Aran and Ignacio Ferreira-González and José Rodríguez-Palomares and Laura Galian-Gay},
journal = {Journal of Clinical Medicine},
year = {2026},
month = nov,
doi = {10.3390/jcm15218588},
url = {https://www.mdpi.com/2077-0383/15/21/8588},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Echocardiographic Parameters in the Assessment of Tricuspid Regurgitation Prognosis: What Is New?
AU - Bianca Rocca
AU - Javier Solsona-Caravaca
AU - Martin Roncaglia
AU - Nuria Vallejo
AU - Víctor González Fernández
AU - Pablo E. Tobías-Castillo
AU - Gisela Teixidó-Tura
AU - Ruper Oliveró-Soldevila
AU - Guillem Casas
AU - Filipa Valente
AU - Oro Aran
AU - Ignacio Ferreira-González
AU - José Rodríguez-Palomares
AU - Laura Galian-Gay
PY - 2026
DA - 2026/11/04
JO - Journal of Clinical Medicine
DO - 10.3390/jcm15218588
UR - https://www.mdpi.com/2077-0383/15/21/8588
AB - Tricuspid regurgitation (TR) is associated with adverse clinical outcomes, highlighting the need for echocardiographic assessment beyond conventional severity grading. This narrative review examines the prognostic value and clinical applicability of established and emerging echocardiographic parameters. TR phenotype influences prognosis and response to transcatheter intervention, with more favourable outcomes in atrial than ventricular functional TR. The five-grade TR classification improves risk stratification, with massive or torrential TR associated with worse outcomes despite comparable procedural success. Right ventricular–pulmonary arterial coupling provides valuable prognostic information and may help identify an optimal therapeutic window for transcatheter intervention, particularly in patients with intermediate coupling values. The GLIDE score helps predict anatomical suitability and procedural success for transcatheter edge-to-edge repair, whereas high TRI-SCORE values (≥6) identify patients in whom a significant survival benefit from repair has not been demonstrated. Treatment decisions should therefore integrate symptoms, overall clinical status, procedural feasibility, and expected benefit through individualized Heart Team assessment. Following intervention, the severity of residual TR, ideally mild or less, remains a key determinant of procedural success.
SN - 2077-0383
ER -