Skip to content
DraconiticResearch
Search Sources API
182,544 studies31 sourcesUpdated 3 min ago
Peer-reviewedCC BY 4.0Actas Españolas de Psiquiatría

Effects of Psychological Counselling Combined With Tolvaptan on Depression, Anxiety, and Quality of Life in Patients With Traumatic Brain Injury and Hyponatremia

  • Yu Wang1
  • Zhiwei Wang2
  • Zhang Xiong1
  • Hanyun Xu1
  1. 1Department of Neurosurgery, First Affiliated Hospital of Wannan Medical College, 241000 Wuhu, Anhui, China
  2. 2Department of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, 230000 Hefei, Anhui, China
Read full textPDFDOICite

Abstract

Background:: To explore the effects of psychological counselling model combined with tolvaptan on depression, anxiety, and quality of life in patients with traumatic brain injury (TBI) and hyponatremia.

Methods:: This retrospective study included 150 patients with TBI complicated by hyponatremia admitted to the First Affiliated Hospital of Wannan Medical College between May 2022 and May 2024. Based on the treatment methods provided in their medical records, the patients were divided into a combined treatment group (n = 75), receiving psychological counselling combined with tolvaptan, and a traditional treatment group (n = 75), receiving tolvaptan alone. Serum sodium levels, depression and anxiety status, quality of life, and self-efficacy were compared between the two groups before and after counselling.

Results:: Compared with the traditional treatment group, the combined treatment group showed better stability in serum sodium recovery, significantly lower depression and anxiety scores, and significantly higher scores in quality of life, self-efficacy, and social functioning than the traditional treatment group (all p < 0.05).

Conclusions:: Among patients with TBI and hyponatremia, psychological counselling combined with tolvaptan was associated with more stable serum sodium recovery, better emotional state and improved quality of life compared with tolvaptan alone. However, due to the retrospective nature of this study, these findings should be interpreted as correlational rather than causal. Prospective controlled studies are needed to further validate these findings.

Related

  1. Persistent SIADH-like Hyponatremia Requiring Tolvaptan Despite Glucocorticoid Replacement in Rathke’s Cleft Cyst-Associated Hypophysitis: A Therapeutic Dilemma
    Yuya Shimizu, Reo Ishii, Kazumasa Tanaka +4
    Internal MedicinePeer-reviewedCC BY-NC-NDFull textGeneral medicineJ-STAGE
  2. Physical and psychological burden in RRMS: depression and fatigue beyond disease duration
    Neslihan Eskut, Ekin Aydin Demir, Asli Koskderelioglu +1
    Arquivos de neuro-psiquiatriaPeer-reviewedCC BYFull textGeneral medicineEurope PMCDOAJ
  3. Psychological processes linking insomnia with depression and anxiety in emerging adulthood
    Amelia Stanton, Qimin Liu, Katherine Kabel +5
    PsyArXivPreprintAll rights reservedFull textPsychiatry & mental healthOSF
  4. Relationships Between Place Identity, Post-Traumatic Stress Symptoms, and Psychological Well-Being After the Earthquake in Hatay
    Gülşen Filazoğlu Çokluk, Feyruz Usluoglu, Meral Atıcı +6
    Psikiyatride Güncel YaklaşımlarPeer-reviewedCC BY-NC-NDFull textPsychiatry & mental healthDOAJ
  5. Childhood traumatic experiences and postpartum depression: a mixed methods narrative study.
    Maria McDonald, Richard Jiang, Sahana Gopi +2
    Archives of women's mental healthPeer-reviewedCC BYFull textEpidemiology & public healthEurope PMC

Cite

BibTeXRIS
BibTeX
@article{wang2026effects,
  title = {{Effects of Psychological Counselling Combined With Tolvaptan on Depression, Anxiety, and Quality of Life in Patients With Traumatic Brain Injury and Hyponatremia}},
  author = {Yu Wang and Zhiwei Wang and Zhang Xiong and Hanyun Xu},
  journal = {Actas Españolas de Psiquiatría},
  year = {2026},
  month = oct,
  doi = {10.62641/aep.2234},
  url = {https://doi.org/10.62641/aep.2234},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Effects of Psychological Counselling Combined With Tolvaptan on Depression, Anxiety, and Quality of Life in Patients With Traumatic Brain Injury and Hyponatremia
AU  - Yu Wang
AU  - Zhiwei Wang
AU  - Zhang Xiong
AU  - Hanyun Xu
PY  - 2026
DA  - 2026/10/15
JO  - Actas Españolas de Psiquiatría
DO  - 10.62641/aep.2234
UR  - https://doi.org/10.62641/aep.2234
AB  - Background:: To explore the effects of psychological counselling model combined with tolvaptan on depression, anxiety, and quality of life in patients with traumatic brain injury (TBI) and hyponatremia.  Methods:: This retrospective study included 150 patients with TBI complicated by hyponatremia admitted to the First Affiliated Hospital of Wannan Medical College between May 2022 and May 2024. Based on the treatment methods provided in their medical records, the patients were divided into a combined treatment group (n = 75), receiving psychological counselling combined with tolvaptan, and a traditional treatment group (n = 75), receiving tolvaptan alone. Serum sodium levels, depression and anxiety status, quality of life, and self-efficacy were compared between the two groups before and after counselling.  Results:: Compared with the traditional treatment group, the combined treatment group showed better stability in serum sodium recovery, significantly lower depression and anxiety scores, and significantly higher scores in quality of life, self-efficacy, and social functioning than the traditional treatment group (all p < 0.05).  Conclusions:: Among patients with TBI and hyponatremia, psychological counselling combined with tolvaptan was associated with more stable serum sodium recovery, better emotional state and improved quality of life compared with tolvaptan alone. However, due to the retrospective nature of this study, these findings should be interpreted as correlational rather than causal. Prospective controlled studies are needed to further validate these findings.
SN  - 1139-9287
SN  - 1578-2735
ER  -