Odontogenic Keratocysts in the Anterior Midline Region: A Case Series and Literature Review.
4 affiliations
- 1Department of Biosciences and Oral Diagnosis Institute of Science and Technology, São Paulo State University (UNESP) São José dos Campos São Paulo Brazil.
- 2Department of Clinical and Preventive Dentistry Federal University of Pernambuco (UFPE) Recife Pernambuco Brazil.
- 3Department of Diagnosis and Surgery Institute of Science and Technology, São Paulo State University (UNESP) São José dos Campos São Paulo Brazil.
- 4Department of Stomatology A. C. Camargo Cancer Center São Paulo São Paulo Brazil.
Abstract
This case series describes three midline odontogenic keratocysts (OKCs) and reviews the associated literature. All three patients were male; two lesions were maxillary. All lesions were surgically excised, with no recurrence. A search of PubMed, Embase, and Scopus identified 33 reported cases of midline OKC, including this series. Of these, 64% (21/33) were male, and age ranged from 6 to 80 years (mean 39.8 ± 20.3). The mandible was affected in 67% (22/33). Excision was the predominant treatment (94%, 31/33), with adjunctive cauterization in 30% (10/33) and decompression in 15% (5/33). Among cases with available follow-up, one recurrence was reported. OKC should be considered in the differential diagnosis of midline jaw lesions, supported by combined clinical, radiographic, and histopathological assessment.
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BibTeX
@article{malta2026odontogenic,
title = {{Odontogenic Keratocysts in the Anterior Midline Region: A Case Series and Literature Review.}},
author = {Isabella Souza Malta and Bruno de Albuquerque Hayasida and Ana Lia Anbinder and Elaine Judite de Amorim Carvalho and Marcelo Marotta Araújo and André Caroli Rocha and Danyel Elias da Cruz Perez and Estela Kaminagakura},
journal = {Clinical case reports},
year = {2026},
month = oct,
doi = {10.1002/ccr3.73749},
url = {https://europepmc.org/article/MED/42910038},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Odontogenic Keratocysts in the Anterior Midline Region: A Case Series and Literature Review.
AU - Isabella Souza Malta
AU - Bruno de Albuquerque Hayasida
AU - Ana Lia Anbinder
AU - Elaine Judite de Amorim Carvalho
AU - Marcelo Marotta Araújo
AU - André Caroli Rocha
AU - Danyel Elias da Cruz Perez
AU - Estela Kaminagakura
PY - 2026
DA - 2026/10/21
JO - Clinical case reports
DO - 10.1002/ccr3.73749
UR - https://europepmc.org/article/MED/42910038
AB - This case series describes three midline odontogenic keratocysts (OKCs) and reviews the associated literature. All three patients were male; two lesions were maxillary. All lesions were surgically excised, with no recurrence. A search of PubMed, Embase, and Scopus identified 33 reported cases of midline OKC, including this series. Of these, 64% (21/33) were male, and age ranged from 6 to 80 years (mean 39.8 ± 20.3). The mandible was affected in 67% (22/33). Excision was the predominant treatment (94%, 31/33), with adjunctive cauterization in 30% (10/33) and decompression in 15% (5/33). Among cases with available follow-up, one recurrence was reported. OKC should be considered in the differential diagnosis of midline jaw lesions, supported by combined clinical, radiographic, and histopathological assessment.
SN - 2050-0904
ER -