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Peer-reviewedCC BY-NCJournal for immunotherapy of cancer

Engineering T cell-engaging bispecific antibodies targeting KRAS G12V neoantigen across HLA-A*11:01 and HLA-A*03:01.

8 affiliations
  1. 1Laboratory of Immunogenomics, Center for Intractable Diseases and ImmunoGenomics (CiDIG), National Institutes of Biomedical Innovation, Health and Nutrition (NIBN), Ibaraki, Osaka, Japan.
  2. 2Project for Immunogenomics, Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan.
  3. 3Laboratory of Biofunctional Molecular Medicine, Center for Drug Design Research (CDDR), National Institutes of Biomedical Innovation, Health and Nutrition (NIBN), Ibaraki, Osaka, Japan.
  4. 4Laboratory of Molecular Diagnostics and Therapeutics, Center for Intractable Diseases and ImmunoGenomics (CiDIG), National Institutes of Biomedical Innovation, Health and Nutrition (NIBN), Ibaraki, Osaka, Japan.
  5. 5Laboratory of In Silico Design, Artificial Intelligence Center for Health and Biomedical Research (ArCHER), National Institutes of Biomedical Innovation, Health and Nutrition (NIBN), Ibaraki, Osaka, Japan.
  6. 6Department of Surgery, Uji-Tokushukai Medical Center, Uji, Kyoto, Japan.
  7. 7Department of Gastroenterological Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan.
  8. 8Laboratory of Immunogenomics, Center for Intractable Diseases and ImmunoGenomics (CiDIG), National Institutes of Biomedical Innovation, Health and Nutrition (NIBN), Ibaraki, Osaka, Japan [email protected].

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BibTeX
@article{wu2026engineering,
  title = {{Engineering T cell-engaging bispecific antibodies targeting KRAS G12V neoantigen across HLA-A*11:01 and HLA-A*03:01.}},
  author = {Xiaojing Wu and Clara Effenberger and Yosuke Matsushita and Hiroki Tanaka and Yu Ishii and Suyong Re and Saki Matsumoto and Satoshi Nagayama and Yusuke Nakamura and Kazuma Kiyotani},
  journal = {Journal for immunotherapy of cancer},
  year = {2026},
  month = oct,
  doi = {10.1136/jitc-2026-016411},
  url = {https://europepmc.org/article/MED/42896875},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - Engineering T cell-engaging bispecific antibodies targeting KRAS G12V neoantigen across HLA-A*11:01 and HLA-A*03:01.
AU  - Xiaojing Wu
AU  - Clara Effenberger
AU  - Yosuke Matsushita
AU  - Hiroki Tanaka
AU  - Yu Ishii
AU  - Suyong Re
AU  - Saki Matsumoto
AU  - Satoshi Nagayama
AU  - Yusuke Nakamura
AU  - Kazuma Kiyotani
PY  - 2026
DA  - 2026/10/18
JO  - Journal for immunotherapy of cancer
DO  - 10.1136/jitc-2026-016411
UR  - https://europepmc.org/article/MED/42896875
SN  - 2051-1426
ER  -