Landing-Energy-Controlled Surface Conformation of Electrosprayed Foldamer Molecules on Au(111)
Abstract
Preserving the structural integrity of biomimetic foldamers upon surface deposition is essential for their integration into functional molecular architectures and devices. When assembled in well-ordered monolayers, these molecules can exhibit distinctive characteristics. In this study, we investigate the electrospray-controlled ion beam deposition of foldamer molecules in an ultrahigh vacuum (UHV) environment on an Au(111) surface and examine how their conformation depends on the mean landing energy during deposition. At a low mean landing energy of about 0.6 eV, intact foldamers are observed on the surface, whereas higher landing energies predominantly result in unfolded molecules and partially folded states. Additionally, annealing of the substrate converts folded conformations into unfolded ones. These results highlight the importance of soft-landing conditions to maintain hydrogen-bond-stabilized architectures on surfaces, offering a model platform for studying the structure–function relationship of surface-supported thermolabile biomolecules.
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BibTeX
@article{zhang2026landingenergycontrolled,
title = {{Landing-Energy-Controlled Surface Conformation of Electrosprayed Foldamer Molecules on Au(111)}},
author = {Shengming Zhang and Dennis Meier and Patrick Lawes and Pengfei Zhao and Jinhua Wang and Victor Maurizot and Andreas Walz and Annette Huettig and Hartmut Schlichting and Anthoula Papageorgiou and Joachim Reichert and Ivan Huc and Johannes Barth},
journal = {ACS Nano},
year = {2026},
month = sep,
doi = {10.1021/acsnano.5c12973},
url = {https://hal.science/hal-05759966v1},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Landing-Energy-Controlled Surface Conformation of Electrosprayed Foldamer Molecules on Au(111)
AU - Shengming Zhang
AU - Dennis Meier
AU - Patrick Lawes
AU - Pengfei Zhao
AU - Jinhua Wang
AU - Victor Maurizot
AU - Andreas Walz
AU - Annette Huettig
AU - Hartmut Schlichting
AU - Anthoula Papageorgiou
AU - Joachim Reichert
AU - Ivan Huc
AU - Johannes Barth
PY - 2026
DA - 2026/09/23
JO - ACS Nano
DO - 10.1021/acsnano.5c12973
UR - https://hal.science/hal-05759966v1
AB - Preserving the structural integrity of biomimetic foldamers upon surface deposition is essential for their integration into functional molecular architectures and devices. When assembled in well-ordered monolayers, these molecules can exhibit distinctive characteristics. In this study, we investigate the electrospray-controlled ion beam deposition of foldamer molecules in an ultrahigh vacuum (UHV) environment on an Au(111) surface and examine how their conformation depends on the mean landing energy during deposition. At a low mean landing energy of about 0.6 eV, intact foldamers are observed on the surface, whereas higher landing energies predominantly result in unfolded molecules and partially folded states. Additionally, annealing of the substrate converts folded conformations into unfolded ones. These results highlight the importance of soft-landing conditions to maintain hydrogen-bond-stabilized architectures on surfaces, offering a model platform for studying the structure–function relationship of surface-supported thermolabile biomolecules.
SN - 1936-0851
SN - 1936-086X
ER -