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Peer-reviewedCC BYOpen forum infectious diseases

First Molecularly Confirmed Case of Leishmania infantum Visceral Leishmaniasis With Concomitant Atypical Cutaneous Disease in Panama in an HIV-Infected Patient.

  • Monica Pachar-Flores1,2,3
  • Franklyn Samudio4,5,6
  • Luis Jaen6
  • José A Suárez3,5,6
6 affiliations
  1. 1Service of Infectious Diseases, Hospital Santo Tomas, Panama, Panama.
  2. 2Infectious Diseases, Instituto Oncologico Nacional, Panama, Panama.
  3. 3InfectoTropico, Panama, Panama.
  4. 4Departamento de Investigación en Parasitología, Instituto Conmemorativo Gorgas de Estudios de la Salud, Panamá, Panama.
  5. 5Sistema Nacional de Investigación (SIN), Investigador Nacional 2, SENACYT, Panamá, Panama.
  6. 6Facultad de Ciencias Naturales y Exactas, University of Panamá, Panama, Panama.
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Abstract

Leishmaniasis in Panama is mainly cutaneous or mucocutaneous. We report the first molecularly confirmed case of Leishmania infantum visceral leishmaniasis in Panama, diagnosed in a Nicaraguan patient with HIV, who had systemic symptoms and a nodular skin lesion. HSP70 PCR sequencing of blood confirmed the species. This case underscores the diagnostic and treatment challenges of visceral leishmaniasis in immunocompromised patients and the importance of molecular species identification.

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Cite

BibTeXRIS
BibTeX
@article{pacharflores2026first,
  title = {{First Molecularly Confirmed Case of Leishmania infantum Visceral Leishmaniasis With Concomitant Atypical Cutaneous Disease in Panama in an HIV-Infected Patient.}},
  author = {Monica Pachar-Flores and Franklyn Samudio and Luis Jaen and José A Suárez},
  journal = {Open forum infectious diseases},
  year = {2026},
  month = oct,
  doi = {10.1093/ofid/ofag648},
  url = {https://europepmc.org/article/MED/43011516},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - First Molecularly Confirmed Case of Leishmania infantum Visceral Leishmaniasis With Concomitant Atypical Cutaneous Disease in Panama in an HIV-Infected Patient.
AU  - Monica Pachar-Flores
AU  - Franklyn Samudio
AU  - Luis Jaen
AU  - José A Suárez
PY  - 2026
DA  - 2026/10/04
JO  - Open forum infectious diseases
DO  - 10.1093/ofid/ofag648
UR  - https://europepmc.org/article/MED/43011516
AB  - Leishmaniasis in Panama is mainly cutaneous or mucocutaneous. We report the first molecularly confirmed case of Leishmania infantum visceral leishmaniasis in Panama, diagnosed in a Nicaraguan patient with HIV, who had systemic symptoms and a nodular skin lesion. HSP70 PCR sequencing of blood confirmed the species. This case underscores the diagnostic and treatment challenges of visceral leishmaniasis in immunocompromised patients and the importance of molecular species identification.
SN  - 2328-8957
ER  -