Skip to content
DraconiticResearch
Search Sources API
189,280 studies31 sourcesUpdated 33 min ago
Peer-reviewedCC BY-NC-NDAnnals of hematology

Florbetaben PET for early and non-invasive diagnosis of light chain amyloidosis: a case report and brief review of the literature.

  • Ilaria Sorgiovanni1
  • Maria Livia Del Giudice2
  • Dario Genovesi3
  • Assuero Giorgetti3
  • Giuseppe Vergaro4
  • Alberto Aimo4
  • Michele Emdin4
  • Sara Galimberti2
  • Gabriele Buda2
4 affiliations
  1. 1Department of Clinical and Experimental Medicine, Hematology Santa Chiara Hospital, University of Pisa, via Roma 67, Pisa, PI, 56126, Italy. [email protected].
  2. 2Department of Clinical and Experimental Medicine, Hematology Santa Chiara Hospital, University of Pisa, via Roma 67, Pisa, PI, 56126, Italy.
  3. 3Division of Nuclear Medicine, Fondazione Toscana Gabriele Monasterio, Pisa, Italy.
  4. 4Cardiology Division, Fondazione Toscana Gabriele Monasterio, Pisa, Italy.
Read full textPDFDOICite

Abstract

Light chain amyloidosis is a hematological disease requiring rapid diagnosis and urgent therapeutic intervention. The confirmation of the clinical suspicion demands invasive methods, in order to demonstrate histological involvement of organs. Substantial efforts are required especially for cardiac localization, because of mimicking conditions and non-specific symptoms. Florbetaben PET is an emerging powerful tool for early and non-invasive diagnosis and for detection of atypical sites of deposits. The present paper reports the case of a 72-year-old man diagnosed with light chain amyloidosis with cardiac and thyroid involvement early identified through this promising imaging technique.

Related

  1. Case Report: Gastrointestinal-onset hereditary transthyretin amyloidosis with cardiomyopathy and equivocal 99mTc-PYP scintigraphy: diagnosis by florbetapir PET-guided skeletal muscle biopsy and genetic testing
    Shida Cai, Shisheng Miao, Guohui Yan +8
    Frontiers in Cardiovascular MedicinePeer-reviewedCC BY 4.0Full textMolecular biology & gene regulationCrossrefEurope PMCPMC
  2. Early diagnosis of capivasertib-associated severe hyperglycemia with diabetic ketosis diagnosed in routine clinical practice: a case report with review of literature
    Masashi Yoshikawa, Keiichiro Takahashi, Satoshi Yoshino +9
    Endocrine JournalPeer-reviewedCC BY-NC-NDFull textMolecular biology & gene regulationJ-STAGE
  3. Systemic AA Amyloidosis Following Immune Checkpoint Inhibitor Therapy for Lung Carcinosarcoma: An Autopsy Case and Review of the Literature
    Shinobu Onishi, Sari Iwasaki, Shimpei Nakagawa +9
    Internal MedicinePeer-reviewedCC BY-NC-NDFull text1 citedMolecular biology & gene regulationJ-STAGE
  4. Cardiac amyloidosis: recognition, diagnosis and management
    Natasha Gorrie, Elyn Montgomery, Georgia McCaughan +2
    Australian PrescriberPeer-reviewedCC BY-NC-ND 4.0Full textMolecular biology & gene regulationPMCEurope PMC
  5. IgM Pleural Amyloidosis Diagnosed by Pleural Effusion Cell Block: A Case Report
    Ayana Suzuki, Takahiro Suzuki, Kakeru Hisakane +7
    Internal MedicinePeer-reviewedCC BY-NC-NDFull textMolecular biology & gene regulationJ-STAGE

Cite

BibTeXRIS
BibTeX
@article{sorgiovanni2026florbetaben,
  title = {{Florbetaben PET for early and non-invasive diagnosis of light chain amyloidosis: a case report and brief review of the literature.}},
  author = {Ilaria Sorgiovanni and Maria Livia Del Giudice and Dario Genovesi and Assuero Giorgetti and Giuseppe Vergaro and Alberto Aimo and Michele Emdin and Sara Galimberti and Gabriele Buda},
  journal = {Annals of hematology},
  year = {2026},
  month = aug,
  doi = {10.1007/s00277-026-06823-6},
  url = {https://europepmc.org/article/MED/42972135},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Florbetaben PET for early and non-invasive diagnosis of light chain amyloidosis: a case report and brief review of the literature.
AU  - Ilaria Sorgiovanni
AU  - Maria Livia Del Giudice
AU  - Dario Genovesi
AU  - Assuero Giorgetti
AU  - Giuseppe Vergaro
AU  - Alberto Aimo
AU  - Michele Emdin
AU  - Sara Galimberti
AU  - Gabriele Buda
PY  - 2026
DA  - 2026/08/05
JO  - Annals of hematology
DO  - 10.1007/s00277-026-06823-6
UR  - https://europepmc.org/article/MED/42972135
AB  - Light chain amyloidosis is a hematological disease requiring rapid diagnosis and urgent therapeutic intervention. The confirmation of the clinical suspicion demands invasive methods, in order to demonstrate histological involvement of organs. Substantial efforts are required especially for cardiac localization, because of mimicking conditions and non-specific symptoms. Florbetaben PET is an emerging powerful tool for early and non-invasive diagnosis and for detection of atypical sites of deposits. The present paper reports the case of a 72-year-old man diagnosed with light chain amyloidosis with cardiac and thyroid involvement early identified through this promising imaging technique.
SN  - 0939-5555
SN  - 1432-0584
ER  -