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Peer-reviewedCC BYJournal for ImmunoTherapy of Cancer

83 Translational PBPK modeling of PET imaging reveals enhanced predicted tumor exposure of antiCTLA4 singledomain antibody fragments vs. monoclonal antibodies

  • Kapil Mayawala1
  • Edward Bowman1
  • Xiangjun Meng2
  • Tapan Nayak3
  • Kerry A Riffel1
  • Daniel J Rubins1
  • Liza Gantert1
  • Tommy Li1
  • Hyking Haley1
  • Mona Purcell1
  • Krista Getty1
  • Dinesh P de Alwis1
1 more authors
  • Julie P Stone1
  1. 1Merck & Co., Inc., Rahway, NJ, USA
  2. 2Shanghai Key Laboratory of Gut Microecology and Associated Major Diseases Research, Digestive Disease Research and Clinical Translation Center, Department of Gastroenterology, Shanghai Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
  3. 3Merck, West Point, PA, USA
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Cite

BibTeXRIS
BibTeX
@article{mayawala2026translational,
  title = {{83 Translational PBPK modeling of PET imaging reveals enhanced predicted tumor exposure of antiCTLA4 singledomain antibody fragments vs. monoclonal antibodies}},
  author = {Kapil Mayawala and Edward Bowman and Xiangjun Meng and Tapan Nayak and Kerry A Riffel and Daniel J Rubins and Liza Gantert and Tommy Li and Hyking Haley and Mona Purcell and Krista Getty and Dinesh P de Alwis and Julie P Stone},
  journal = {Journal for ImmunoTherapy of Cancer},
  year = {2026},
  month = nov,
  doi = {10.1136/jitc-2026-sitc2026.0083},
  url = {https://doi.org/10.1136/jitc-2026-sitc2026.0083},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - 83 Translational PBPK modeling of PET imaging reveals enhanced predicted tumor exposure of antiCTLA4 singledomain antibody fragments vs. monoclonal antibodies
AU  - Kapil Mayawala
AU  - Edward Bowman
AU  - Xiangjun Meng
AU  - Tapan Nayak
AU  - Kerry A Riffel
AU  - Daniel J Rubins
AU  - Liza Gantert
AU  - Tommy Li
AU  - Hyking Haley
AU  - Mona Purcell
AU  - Krista Getty
AU  - Dinesh P de Alwis
AU  - Julie P Stone
PY  - 2026
DA  - 2026/11/07
JO  - Journal for ImmunoTherapy of Cancer
DO  - 10.1136/jitc-2026-sitc2026.0083
UR  - https://doi.org/10.1136/jitc-2026-sitc2026.0083
SN  - 2051-1426
ER  -