Knowledge of human monkeypox among people living with HIV during the monkeypox epidemic in China : A cross-sectional study
- 1Department of Clinical Laboratory, Hangzhou Xixi Hospital, Zhejiang, China
- 2Infection Department, Hangzhou Xixi Hospital, Zhejiang, China
- 3Department of Clinical Laboratory, The 903rd Hospital of PLA, Zhejiang, China.
Abstract
The monkeypox knowledge among people living with HIV (PLHIV) remains largely unexplored, particularly concerning the ongoing monkeypox outbreak. This research aims to investigate the level of monkeypox knowledge and its associated correlates. This cross-sectional study was conducted within HIV outpatient clinics from July 26 to August 31, 2023. The validated questionnaire encompassed 4 domains: basic demographic information, sexual behavior, attitudes toward monkeypox, and knowledge of monkeypox. Univariable and multivariable logistic regression models examined the factors influencing monkeypox knowledge. Of the 910 HIV-positive patients included in the final analysis, the median age was 34 years (interquartile range 29–41), 884 (97.1%) were male, and 460 (50.5%) HIV-positive patients demonstrated knowledge of monkeypox. Patients with a junior college or undergraduate education level (adjusted odds ratio [aOR]: 3.57, 95% CI: 2.51–5.06, P < .001) and those with a master’s degree or above (aOR: 3.75, 95% CI: 1.98–7.10, P < .001) were more likely to possess knowledge of monkeypox than patients with a high school education or below. Additionally, patients who expressed general concern (aOR: 6.02, 95% CI: 3.43–10.55, P < .001) or very concern (aOR: 12.89, 95% CI: 7.09–23.44, P < .001) regarding the monkeypox epidemic were more likely to possess knowledge of monkeypox than those who were not concerned. HIV patients who completed the questionnaire in Phase 2 were more likely to have monkeypox knowledge than those in Phase 1. Half of the PLHIV demonstrated a satisfactory level of monkeypox knowledge in the context of the monkeypox epidemic in China. Notably, individuals with higher levels of education, greater concern for monkeypox, and those who completed the questionnaire in Phase 2 exhibited a higher likelihood of possessing monkeypox knowledge. Public health strategies should prioritize raising awareness among PLHIV regarding the potential risks associated with monkeypox and actively disseminate knowledge about the disease through diverse channels to mitigate its transmission.
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BibTeX
@article{zuo2026knowledge,
title = {{Knowledge of human monkeypox among people living with HIV during the monkeypox epidemic in China : A cross-sectional study}},
author = {Zhongbao Zuo and Dingyan Yan and Chunli Yang and Miaochan Wang and Jie Han and Yali Hu and Jing Wu and Aifang Xu and Mengyan Wang and Guoxiang Zheng},
journal = {Medicine},
year = {2026},
month = oct,
doi = {10.1097/md.0000000000051081},
url = {https://europepmc.org/article/PMC/PMC13727262},
note = {CC BY-NC},
}
RIS
TY - JOUR
TI - Knowledge of human monkeypox among people living with HIV during the monkeypox epidemic in China : A cross-sectional study
AU - Zhongbao Zuo
AU - Dingyan Yan
AU - Chunli Yang
AU - Miaochan Wang
AU - Jie Han
AU - Yali Hu
AU - Jing Wu
AU - Aifang Xu
AU - Mengyan Wang
AU - Guoxiang Zheng
PY - 2026
DA - 2026/10/30
JO - Medicine
DO - 10.1097/md.0000000000051081
UR - https://europepmc.org/article/PMC/PMC13727262
AB - The monkeypox knowledge among people living with HIV (PLHIV) remains largely unexplored, particularly concerning the ongoing monkeypox outbreak. This research aims to investigate the level of monkeypox knowledge and its associated correlates. This cross-sectional study was conducted within HIV outpatient clinics from July 26 to August 31, 2023. The validated questionnaire encompassed 4 domains: basic demographic information, sexual behavior, attitudes toward monkeypox, and knowledge of monkeypox. Univariable and multivariable logistic regression models examined the factors influencing monkeypox knowledge. Of the 910 HIV-positive patients included in the final analysis, the median age was 34 years (interquartile range 29–41), 884 (97.1%) were male, and 460 (50.5%) HIV-positive patients demonstrated knowledge of monkeypox. Patients with a junior college or undergraduate education level (adjusted odds ratio [aOR]: 3.57, 95% CI: 2.51–5.06, P < .001) and those with a master’s degree or above (aOR: 3.75, 95% CI: 1.98–7.10, P < .001) were more likely to possess knowledge of monkeypox than patients with a high school education or below. Additionally, patients who expressed general concern (aOR: 6.02, 95% CI: 3.43–10.55, P < .001) or very concern (aOR: 12.89, 95% CI: 7.09–23.44, P < .001) regarding the monkeypox epidemic were more likely to possess knowledge of monkeypox than those who were not concerned. HIV patients who completed the questionnaire in Phase 2 were more likely to have monkeypox knowledge than those in Phase 1. Half of the PLHIV demonstrated a satisfactory level of monkeypox knowledge in the context of the monkeypox epidemic in China. Notably, individuals with higher levels of education, greater concern for monkeypox, and those who completed the questionnaire in Phase 2 exhibited a higher likelihood of possessing monkeypox knowledge. Public health strategies should prioritize raising awareness among PLHIV regarding the potential risks associated with monkeypox and actively disseminate knowledge about the disease through diverse channels to mitigate its transmission.
SN - 0304-5412
SN - 1536-5964
SN - 0025-7974
ER -