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Peer-reviewedCC BYJAMA Network Open

Orthostatic Autonomic Dysregulation and Orthostatic Intolerance Following Adult Concussion

  • Veronik Sicard1
  • Courtney Kennedy2
  • Lauren Xinyue Duan3
  • Andrée-Anne Ledoux3,4,5,6
  • John J. Leddy7
  • Kim Connelly8,9
  • Achelle Cortel-LeBlanc10,11
  • Stephen A. Kutcher3
  • Lawrence Richer12
  • Richard J. Webster3,13
  • Charlotte Anderson14,15
  • Sharon Johnston10,16
16 more authors
  • Roger Leonard Zemek3,17
  • uOttawa Brain-Heart Interconnectome (BHI) and TRANSCENDENT Concussion Integrated Discovery Programs
  • Noah Silverberg18
  • Keith Owen Yeates18
  • Monica Lamoureux18
  • Lisa Albrecht18
  • Andrew Dodd18
  • Ewa Sucha18
  • Ivan Terekhov18
  • Jacqueline van Ierssel18
  • Andra Smith18
  • Jennifer Reed18
  • Lisa Walker18
  • Rebekah Mannix18
  • Christina Master18
  • Steven Hicks18
18 affiliations
  1. 1Faculty of Nursing, Université Laval, Québec, Québec, Canada
  2. 2Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada
  3. 3Children’s Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada
  4. 4University of Ottawa Brain and Mind Research Institute, University of Ottawa, Ottawa, Ontario, Canada
  5. 5Department of Neuroscience, Carleton University, Ottawa, Ontario, Canada
  6. 6Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada
  7. 7UBMD Department of Orthopaedics and Sports Medicine, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo
  8. 8Keenan Research Center for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael’s Hospital, Unity Health Toronto, University of Toronto, Toronto, Ontario, Canada
  9. 9Division of Cardiology, St Michael’s Hospital, Unity Health Toronto, University of Toronto, Toronto, Ontario, Canada
  10. 10Institut du Savoir Montfort, Ottawa, Ontario, Canada
  11. 11Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
  12. 12Women and Children’s Health Research Institute and Faculty of Medicine and Dentistry, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada
  13. 13Telfer School of Medicine, University of Ottawa, Ottawa, Ontario, Canada
  14. 14Alpha Health Services, Toronto, Ontario, Canada
  15. 15Department of Physiotherapy, University of Toronto, Ontario, Canada.
  16. 16Department of Family Medicine, University of Ottawa, Ottawa, Ontario, Canada
  17. 17Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada
  18. 18for the uOttawa Brain-Heart Interconnectome (BHI) and TRANSCENDENT Concussion Integrated Discovery Programs
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Abstract

This cohort study examines the prevalence and co-occurrence of autonomic dysregulation and orthostatic intolerance among adults with concussion and explores associated demographic and injury-related factors.

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Cite

BibTeXRIS
BibTeX
@article{sicard2026orthostatic,
  title = {{Orthostatic Autonomic Dysregulation and Orthostatic Intolerance Following Adult Concussion}},
  author = {Veronik Sicard and Courtney Kennedy and Lauren Xinyue Duan and Andrée-Anne Ledoux and John J. Leddy and Kim Connelly and Achelle Cortel-LeBlanc and Stephen A. Kutcher and Lawrence Richer and Richard J. Webster and Charlotte Anderson and Sharon Johnston and Roger Leonard Zemek and uOttawa Brain-Heart Interconnectome (BHI) and TRANSCENDENT Concussion Integrated Discovery Programs and Noah Silverberg and Keith Owen Yeates and Monica Lamoureux and Lisa Albrecht and Andrew Dodd and Ewa Sucha and Ivan Terekhov and Jacqueline van Ierssel and Andra Smith and Jennifer Reed and Lisa Walker and Rebekah Mannix and Christina Master and Steven Hicks},
  journal = {JAMA Network Open},
  year = {2026},
  month = oct,
  doi = {10.1001/jamanetworkopen.2026.41160},
  url = {https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2855703},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Orthostatic Autonomic Dysregulation and Orthostatic Intolerance Following Adult Concussion
AU  - Veronik Sicard
AU  - Courtney Kennedy
AU  - Lauren Xinyue Duan
AU  - Andrée-Anne Ledoux
AU  - John J. Leddy
AU  - Kim Connelly
AU  - Achelle Cortel-LeBlanc
AU  - Stephen A. Kutcher
AU  - Lawrence Richer
AU  - Richard J. Webster
AU  - Charlotte Anderson
AU  - Sharon Johnston
AU  - Roger Leonard Zemek
AU  - uOttawa Brain-Heart Interconnectome (BHI) and TRANSCENDENT Concussion Integrated Discovery Programs
AU  - Noah Silverberg
AU  - Keith Owen Yeates
AU  - Monica Lamoureux
AU  - Lisa Albrecht
AU  - Andrew Dodd
AU  - Ewa Sucha
AU  - Ivan Terekhov
AU  - Jacqueline van Ierssel
AU  - Andra Smith
AU  - Jennifer Reed
AU  - Lisa Walker
AU  - Rebekah Mannix
AU  - Christina Master
AU  - Steven Hicks
PY  - 2026
DA  - 2026/10/01
JO  - JAMA Network Open
DO  - 10.1001/jamanetworkopen.2026.41160
UR  - https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2855703
AB  - This cohort study examines the prevalence and co-occurrence of autonomic dysregulation and orthostatic intolerance among adults with concussion and explores associated demographic and injury-related factors.
SN  - 2574-3805
ER  -