Agreement Between Immediate and Six-Week Postpartum Testing for Detecting Abnormal Glucose Tolerance in Women with Gestational Diabetes Mellitus.
- 1Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
- 2Fetal Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Abstract
Objective
To evaluate the prevalence of abnormal glucose tolerance at six weeks postpartum among women with gestational diabetes mellitus (GDM) and to evaluate the agreement between early postpartum and six-week postpartum oral glucose tolerance test (GTT).Methods
This prospective repeated-measures study included Thai women with singleton pregnancies, no pregestational diabetes, and a diagnosis of GDM. Participants were consecutively recruited upon admission to the labor and delivery unit. All participants underwent a 75 g, 2-hour GTT both during the immediate postpartum prior to hospital discharge and at six weeks postpartum. Glucose tolerance status was categorized as normal glucose tolerance and abnormal GTT. Agreement between the two testing periods was evaluated using Cohen's kappa coefficient.Results
A total of 158 women were included in the analysis. The prevalence of abnormal glucose tolerance at six weeks postpartum was 44.9% (71/158), including impaired GTT in 66 women (41.8%) and diabetes mellitus in 5 women (3.2%). Among women with abnormal GTT at six weeks postpartum, 42.3% (30/71) had normal early postpartum results. Conversely, 44.6% (33/74) of women with abnormal early postpartum findings demonstrated normal GTT at six weeks. The Cohen's kappa coefficient was 0.197, indicating poor agreement. Agreement for diabetes mellitus diagnosis was similarly low (kappa = 0.201).Conclusion
Early postpartum OGTT demonstrated poor agreement with six-week postpartum testing and showed limited utility as a standalone screening strategy for postpartum dysglycemia among women with GDM. Early postpartum testing may not accurately reflect glycemic status at 6 weeks postpartum, potentially leading to misclassification.
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BibTeX
@article{chunsanit2026agreement,
title = {{Agreement Between Immediate and Six-Week Postpartum Testing for Detecting Abnormal Glucose Tolerance in Women with Gestational Diabetes Mellitus.}},
author = {Supitcha Chunsanit and Threebhorn Kamlungkuea and Phudit Jatavan and Theera Tongsong},
journal = {International journal of women's health},
year = {2026},
month = oct,
doi = {10.2147/ijwh.s651316},
url = {https://europepmc.org/article/MED/42968973},
note = {CC BY-NC},
}
RIS
TY - JOUR
TI - Agreement Between Immediate and Six-Week Postpartum Testing for Detecting Abnormal Glucose Tolerance in Women with Gestational Diabetes Mellitus.
AU - Supitcha Chunsanit
AU - Threebhorn Kamlungkuea
AU - Phudit Jatavan
AU - Theera Tongsong
PY - 2026
DA - 2026/10/28
JO - International journal of women's health
DO - 10.2147/ijwh.s651316
UR - https://europepmc.org/article/MED/42968973
AB - Objective To evaluate the prevalence of abnormal glucose tolerance at six weeks postpartum among women with gestational diabetes mellitus (GDM) and to evaluate the agreement between early postpartum and six-week postpartum oral glucose tolerance test (GTT).Methods This prospective repeated-measures study included Thai women with singleton pregnancies, no pregestational diabetes, and a diagnosis of GDM. Participants were consecutively recruited upon admission to the labor and delivery unit. All participants underwent a 75 g, 2-hour GTT both during the immediate postpartum prior to hospital discharge and at six weeks postpartum. Glucose tolerance status was categorized as normal glucose tolerance and abnormal GTT. Agreement between the two testing periods was evaluated using Cohen's kappa coefficient.Results A total of 158 women were included in the analysis. The prevalence of abnormal glucose tolerance at six weeks postpartum was 44.9% (71/158), including impaired GTT in 66 women (41.8%) and diabetes mellitus in 5 women (3.2%). Among women with abnormal GTT at six weeks postpartum, 42.3% (30/71) had normal early postpartum results. Conversely, 44.6% (33/74) of women with abnormal early postpartum findings demonstrated normal GTT at six weeks. The Cohen's kappa coefficient was 0.197, indicating poor agreement. Agreement for diabetes mellitus diagnosis was similarly low (kappa = 0.201).Conclusion Early postpartum OGTT demonstrated poor agreement with six-week postpartum testing and showed limited utility as a standalone screening strategy for postpartum dysglycemia among women with GDM. Early postpartum testing may not accurately reflect glycemic status at 6 weeks postpartum, potentially leading to misclassification.
SN - 1179-1411
ER -