Characteristics and outcomes of ICU patients with bacterial catheter-associated urinary tract infection
- 1Department of Anaesthesiology and Intensive Care, Medical University of Bialystok, Bialystok, Poland
- 2Medical University of Bialystok, Bialystok, Poland
- 3Department of Emergency Medicine, Medical University of Bialystok, Bialystok, Poland
Abstract
Background: Catheter-associated urinary tract infection (CAUTI) is a common device-associated complication in intensive care units (ICUs). Objective: To characterize bacterial CAUTI in an ICU cohort and identify independent associations with demographic and clinical characteristics available at or before ICU admission. Methods: This single-center retrospective cohort included 3326 index ICU admissions from January 2017 through June 2023. After exclusion of 95 fungal-only clinically classified cases, 3231 records remained. Bacterial CAUTI required compatible clinical findings, at least 48 hours of catheter exposure, and ≥10³ CFU/mL of one or two bacterial species. All patients were catheterized throughout the observed ICU stay. The primary logistic model included only admission characteristics; ICU stay/catheter duration was descriptive because exact CAUTI onset dates were unavailable. Skewed biomarkers were summarized with medians, interquartile ranges, and Mann-Whitney tests. Results: Bacterial CAUTI occurred in 301 patients (9.3%; 95% CI 8.4%−10.4%). Mean ICU stay/catheter duration was 28.3 versus 13.6 days (difference 14.8 days; 95% CI 11.7–17.8), but duration was not interpreted as an independent risk estimate. Mortality was 49.2% versus 45.9% (risk difference 3.2 percentage points; 95% CI −2.7 to 9.1), and bacterial CAUTI was not associated with death after adjustment for admission characteristics (OR 0.95; 95% CI 0.75–1.22). Female sex (OR 1.48; 95% CI 1.15–1.90), obesity (OR 1.62; 95% CI 1.20–2.19), and COVID-19 (OR 2.16; 95% CI 1.55–3.00) were independently associated. At least one resistance phenotype was recorded in 200 patients (66.4%). Conclusions: Bacterial CAUTI was associated with a distinct admission profile and longer observed ICU stay/catheter exposure, although causal direction could not be determined. It was not associated with adjusted in-hospital mortality.
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BibTeX
@article{bartoszewicz2026characteristics,
title = {{Characteristics and outcomes of ICU patients with bacterial catheter-associated urinary tract infection}},
author = {Mateusz Bartoszewicz and Marta Krysik and Sławomir Lech Czaban and Jerzy Robert Ładny},
journal = {PLOS One},
year = {2026},
month = sep,
doi = {10.1371/journal.pone.0358796},
url = {https://doi.org/10.1371/journal.pone.0358796},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Characteristics and outcomes of ICU patients with bacterial catheter-associated urinary tract infection
AU - Mateusz Bartoszewicz
AU - Marta Krysik
AU - Sławomir Lech Czaban
AU - Jerzy Robert Ładny
PY - 2026
DA - 2026/09/25
JO - PLOS One
DO - 10.1371/journal.pone.0358796
UR - https://doi.org/10.1371/journal.pone.0358796
AB - Background: Catheter-associated urinary tract infection (CAUTI) is a common device-associated complication in intensive care units (ICUs). Objective: To characterize bacterial CAUTI in an ICU cohort and identify independent associations with demographic and clinical characteristics available at or before ICU admission. Methods: This single-center retrospective cohort included 3326 index ICU admissions from January 2017 through June 2023. After exclusion of 95 fungal-only clinically classified cases, 3231 records remained. Bacterial CAUTI required compatible clinical findings, at least 48 hours of catheter exposure, and ≥10³ CFU/mL of one or two bacterial species. All patients were catheterized throughout the observed ICU stay. The primary logistic model included only admission characteristics; ICU stay/catheter duration was descriptive because exact CAUTI onset dates were unavailable. Skewed biomarkers were summarized with medians, interquartile ranges, and Mann-Whitney tests. Results: Bacterial CAUTI occurred in 301 patients (9.3%; 95% CI 8.4%−10.4%). Mean ICU stay/catheter duration was 28.3 versus 13.6 days (difference 14.8 days; 95% CI 11.7–17.8), but duration was not interpreted as an independent risk estimate. Mortality was 49.2% versus 45.9% (risk difference 3.2 percentage points; 95% CI −2.7 to 9.1), and bacterial CAUTI was not associated with death after adjustment for admission characteristics (OR 0.95; 95% CI 0.75–1.22). Female sex (OR 1.48; 95% CI 1.15–1.90), obesity (OR 1.62; 95% CI 1.20–2.19), and COVID-19 (OR 2.16; 95% CI 1.55–3.00) were independently associated. At least one resistance phenotype was recorded in 200 patients (66.4%). Conclusions: Bacterial CAUTI was associated with a distinct admission profile and longer observed ICU stay/catheter exposure, although causal direction could not be determined. It was not associated with adjusted in-hospital mortality.
SN - 1932-6203
ER -