Atraumatic iliopsoas heterotopic ossification with postoperative atypical haemolytic uraemic syndrome
- 1Department of Orthopaedics, Datta Meghe Institute of Higher Education and Research Deemed to be University, Wardha, Maharashtra, India
- 2KLE Academy of Higher Education & Research, Belagavi, Karnataka, India
Abstract
We describe a case of a middle-aged woman presenting with a 2-year history of progressive, painless restriction of left hip movement without preceding trauma or surgery. Imaging demonstrated a well-defined ossified mass within the iliopsoas muscle exhibiting a classical zonal maturation pattern. Following unsuccessful conservative therapy, delayed surgical excision after radiological maturation was undertaken and histopathology confirmed heterotopic ossification. On postoperative day 3, she developed acute anaemia, thrombocytopenia and severe renal impairment. Laboratory evaluation supported thrombotic microangiopathy, with atypical haemolytic uraemic syndrome considered the most probable diagnosis. The patient was managed with therapeutic plasma exchange and temporary haemodialysis, resulting in full haematological and renal recovery. At follow-up, hip function improved substantially with no evidence of recurrence. This case emphasises the need to recognise uncommon atraumatic iliopsoas heterotopic ossification and to maintain vigilance for postoperative thrombotic microangiopathy to ensure early multidisciplinary intervention and favourable outcomes.
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BibTeX
@article{dhankhar2026atraumatic,
title = {{Atraumatic iliopsoas heterotopic ossification with postoperative atypical haemolytic uraemic syndrome}},
author = {Kunal Dhankhar and Sandeep Shrivastava and Neelaksh Kumar and Trish Shetty},
journal = {BMJ Case Reports},
year = {2026},
month = oct,
doi = {10.1136/bcr-2026-272969},
url = {https://doi.org/10.1136/bcr-2026-272969},
note = {CC BY-NC 4.0},
}
RIS
TY - JOUR
TI - Atraumatic iliopsoas heterotopic ossification with postoperative atypical haemolytic uraemic syndrome
AU - Kunal Dhankhar
AU - Sandeep Shrivastava
AU - Neelaksh Kumar
AU - Trish Shetty
PY - 2026
DA - 2026/10/28
JO - BMJ Case Reports
DO - 10.1136/bcr-2026-272969
UR - https://doi.org/10.1136/bcr-2026-272969
AB - We describe a case of a middle-aged woman presenting with a 2-year history of progressive, painless restriction of left hip movement without preceding trauma or surgery. Imaging demonstrated a well-defined ossified mass within the iliopsoas muscle exhibiting a classical zonal maturation pattern. Following unsuccessful conservative therapy, delayed surgical excision after radiological maturation was undertaken and histopathology confirmed heterotopic ossification. On postoperative day 3, she developed acute anaemia, thrombocytopenia and severe renal impairment. Laboratory evaluation supported thrombotic microangiopathy, with atypical haemolytic uraemic syndrome considered the most probable diagnosis. The patient was managed with therapeutic plasma exchange and temporary haemodialysis, resulting in full haematological and renal recovery. At follow-up, hip function improved substantially with no evidence of recurrence. This case emphasises the need to recognise uncommon atraumatic iliopsoas heterotopic ossification and to maintain vigilance for postoperative thrombotic microangiopathy to ensure early multidisciplinary intervention and favourable outcomes.
SN - 1757-790X
ER -