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Peer-reviewedCC BYInterventional pain medicine

Concurrent basivertebral nerve radiofrequency ablation and vertebral augmentation as part of a multimodal palliative plan for pathological vertebral compression fracture from spine tumor: A case series of three patients.

  • Shannon Dwyer1
  • Allyson Kouche1
  • Yu-Tung Chen1
  • Jimmy Wen2,3
  • Arsh Alam4
  • Jose Silva5
  • Foad Elahi6
6 affiliations
  1. 1California Northstate University College of Medicine, United States.
  2. 2Highland Hospital, Department of Medicine, United States.
  3. 3Stanford University, Departments of Orthopaedic Surgery and Neurosurgery, United States.
  4. 4University of California, Davis, United States.
  5. 5Sutter Roseville, Department of Emergency Medicine, United States.
  6. 6California Center of Pain Medicine & Rehabilitation, United States.
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Abstract

Pathological vertebral compression fractures from spinal tumors are a source of severe back pain and functional disability. Vertebral augmentation (VA) has been utilized for mechanical stabilization; however, pain may persist due to nociceptive signaling from the basivertebral nerve (BVN). BVN radiofrequency ablation (BVNRFA) has shown efficacy for vertebrogenic back pain associated with Modic changes, but its efficacy for oncologic/pathologic fractures remains an area of exploration. We present a case series of three patients with pathological vertebral compression fractures secondary to spinal tumors who underwent concurrent BVNRFA and VA. All three patients experienced immediate and sustained pain reduction with improvements in function. No peri- or post-procedural complications were observed at one-month follow-up. Concurrent BVNRFA and VA is a novel and synergistic approach that may provide an additional option for select patients with pathological vertebral compression fractures from a spinal tumor within palliative and interventional pain settings. Larger studies are required to clarify ideal patient selection, duration of benefit, and safety.

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Cite

BibTeXRIS
BibTeX
@article{dwyer2026concurrent,
  title = {{Concurrent basivertebral nerve radiofrequency ablation and vertebral augmentation as part of a multimodal palliative plan for pathological vertebral compression fracture from spine tumor: A case series of three patients.}},
  author = {Shannon Dwyer and Allyson Kouche and Yu-Tung Chen and Jimmy Wen and Arsh Alam and Jose Silva and Foad Elahi},
  journal = {Interventional pain medicine},
  year = {2026},
  month = oct,
  doi = {10.1016/j.inpm.2026.100830},
  url = {https://europepmc.org/article/MED/42999649},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Concurrent basivertebral nerve radiofrequency ablation and vertebral augmentation as part of a multimodal palliative plan for pathological vertebral compression fracture from spine tumor: A case series of three patients.
AU  - Shannon Dwyer
AU  - Allyson Kouche
AU  - Yu-Tung Chen
AU  - Jimmy Wen
AU  - Arsh Alam
AU  - Jose Silva
AU  - Foad Elahi
PY  - 2026
DA  - 2026/10/30
JO  - Interventional pain medicine
DO  - 10.1016/j.inpm.2026.100830
UR  - https://europepmc.org/article/MED/42999649
AB  - Pathological vertebral compression fractures from spinal tumors are a source of severe back pain and functional disability. Vertebral augmentation (VA) has been utilized for mechanical stabilization; however, pain may persist due to nociceptive signaling from the basivertebral nerve (BVN). BVN radiofrequency ablation (BVNRFA) has shown efficacy for vertebrogenic back pain associated with Modic changes, but its efficacy for oncologic/pathologic fractures remains an area of exploration. We present a case series of three patients with pathological vertebral compression fractures secondary to spinal tumors who underwent concurrent BVNRFA and VA. All three patients experienced immediate and sustained pain reduction with improvements in function. No peri- or post-procedural complications were observed at one-month follow-up. Concurrent BVNRFA and VA is a novel and synergistic approach that may provide an additional option for select patients with pathological vertebral compression fractures from a spinal tumor within palliative and interventional pain settings. Larger studies are required to clarify ideal patient selection, duration of benefit, and safety.
SN  - 2772-5944
ER  -