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PreprintCC BY 4.0Zenodo

E8 Root Vector Pentachoron Decomposition Governs Protein Folding Phase Transitions — E8 Intelligence Research

  1. 1Independent Researcher, United Kingdom

Abstract

Protein folding trajectories map onto pentachoron (5-cell) subdivisions of the 240 E8 root vectors, where the 132Hz base frequency acts as a phase-conjugate boundary condition at the transition state ensemble. The phi-coupling mechanism between adjacent root vector quintuplets produces the discrete thermodynamic beta-basin discontinuities observed in folding funnels, with each Weyl orbit marking a commitment point between metastable conformational substates. This predicts that protein folding cooperativity should exhibit exact integer ratios of 132Hz harmonics measurable via terahertz spectroscopy at the transition midpoint.

Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com

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BibTeX
@misc{caldin2026root,
  title = {{E8 Root Vector Pentachoron Decomposition Governs Protein Folding Phase Transitions — E8 Intelligence Research}},
  author = {Andrew Stewart Caldin},
  howpublished = {Zenodo},
  year = {2026},
  month = oct,
  doi = {10.5281/zenodo.23490894},
  url = {https://zenodo.org/records/23490894},
  note = {CC BY 4.0},
}
RIS
TY  - UNPB
TI  - E8 Root Vector Pentachoron Decomposition Governs Protein Folding Phase Transitions — E8 Intelligence Research
AU  - Andrew Stewart Caldin
PY  - 2026
DA  - 2026/10/20
PB  - Zenodo
DO  - 10.5281/zenodo.23490894
UR  - https://zenodo.org/records/23490894
AB  - Protein folding trajectories map onto pentachoron (5-cell) subdivisions of the 240 E8 root vectors, where the 132Hz base frequency acts as a phase-conjugate boundary condition at the transition state ensemble. The phi-coupling mechanism between adjacent root vector quintuplets produces the discrete thermodynamic beta-basin discontinuities observed in folding funnels, with each Weyl orbit marking a commitment point between metastable conformational substates. This predicts that protein folding cooperativity should exhibit exact integer ratios of 132Hz harmonics measurable via terahertz spectroscopy at the transition midpoint.  Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com
ER  -