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Peer-reviewedCC BY-NC-NDInternal Medicine

Organizing Pneumonia in a Patient with Pulmonary Transthyretin Amyloidosis

  • Yutaka Tojo
  • Zenta Watanuki
  • Junko Sakurada
  • Teruyuki Satoh
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Abstract

An 86-year-old man who was a retired tunnel construction worker with pleural plaques and chronic pleural effusion was referred for an evaluation of newly developed pulmonary infiltrates. A transbronchial lung biopsy revealed organizing pneumonia with transthyretin amyloid deposition in the alveolar septa. Genetic testing confirmed wild-type transthyretin amyloidosis. Corticosteroid therapy led to partial resolution of the pulmonary infiltrates. Few cases of pulmonary transthyretin amyloidosis associated with organizing pneumonia have been reported. This case highlights the potential involvement of transthyretin amyloidosis in the development of organizing pneumonia.

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Cite

BibTeXRIS
BibTeX
@article{tojo2026organizing,
  title = {{Organizing Pneumonia in a Patient with Pulmonary Transthyretin Amyloidosis}},
  author = {Yutaka Tojo and Zenta Watanuki and Junko Sakurada and Teruyuki Satoh},
  journal = {Internal Medicine},
  year = {2026},
  month = sep,
  doi = {10.2169/internalmedicine.6769-25},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/65/18/65_6769-25/_article},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Organizing Pneumonia in a Patient with Pulmonary Transthyretin Amyloidosis
AU  - Yutaka Tojo
AU  - Zenta Watanuki
AU  - Junko Sakurada
AU  - Teruyuki Satoh
PY  - 2026
DA  - 2026/09/15
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.6769-25
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/65/18/65_6769-25/_article
AB  - An 86-year-old man who was a retired tunnel construction worker with pleural plaques and chronic pleural effusion was referred for an evaluation of newly developed pulmonary infiltrates. A transbronchial lung biopsy revealed organizing pneumonia with transthyretin amyloid deposition in the alveolar septa. Genetic testing confirmed wild-type transthyretin amyloidosis. Corticosteroid therapy led to partial resolution of the pulmonary infiltrates. Few cases of pulmonary transthyretin amyloidosis associated with organizing pneumonia have been reported. This case highlights the potential involvement of transthyretin amyloidosis in the development of organizing pneumonia.
SN  - 1349-7235
SN  - 0918-2918
ER  -