Skip to content
DraconiticResearch
Search Sources API
197,693 studies31 sourcesUpdated 12 min ago
Peer-reviewedCC BY 4.0Emerging Infectious Diseases

Serologic Testing for Middle East Respiratory Syndrome Coronavirus and SARS-CoV-2 Cross-Reactive Immune Responses, the Netherlands

  • Merel R. te Marvelde
  • Anna Z. Mykytyn
  • Matthijs P. Raadsen
  • Alexandre H.J. Bouffier
  • Sivana Baptista Varela
  • Rory D. de Vries
  • Corine H. GeurtsvanKessel
  • Bart L. Haagmans
Read full textDOICite

Abstract

Cross-reactive SARS-CoV-2–specific antibodies could compromise the specificity of MERS-CoV serology, potentially leading to misclassification of infection history. SARS-CoV-2 exposure induced MERS-CoV antibodies primarily targeting the conserved S2 domain, with occasional neutralizing capacity. Combining MERS-CoV S1 binding with neutralization, however, limited the influence of SARS-CoV-2–induced cross-reactivity on MERS-CoV serology.

Related

  1. Middle East Respiratory Syndrome Coronavirus in Camels, Kazakhstan, 2025
    Aidyn Kydyrmanov, Yermukhammet Kassymbekov, Sardor Nuralibekov +5
    Emerging Infectious DiseasesPeer-reviewedCC BY 4.0Full textInfectious diseaseDOAJPMC
  2. Global Genomic Surveillance of Middle East Respiratory Syndrome Coronavirus
    James Richard Otieno, Ahmed Mohammed Albarraq, Francis Amirtharaj Selvaraj +14
    Emerging Infectious DiseasesPeer-reviewedCC BY 4.0Full textInfectious diseaseDOAJPMC
  3. Overlapping Post-COVID Conditions: A Case of Myalgic Encephalomyelitis and Postural Orthostatic Tachycardia Syndrome Triggered by Sequential Epstein-Barr Virus (EBV) and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infections.
    Virgínia R Mayrink Magalhães, Laura A Ribeiro Oliveira, Adelina J Lourenço +11
    CureusPeer-reviewedCC BYFull textNeurologyEurope PMC
  4. Post-treatment serologic, cerebrospinal fluid, MRI, and salivary antibody responses in HIV-negative neurosyphilis: a retrospective study
    Xuan Long, Weipeng Lin, Jiahui Shen +3
    Frontiers in neurologyPeer-reviewedCC BYFull textNeurologyEurope PMC
  5. BRASH syndrome in acute coronavirus disease 2019 myocarditis and acute kidney injury: The importance of early recognition of an iatrogenic spiral.
    Adrija Mehta, Sai Allu, Nassim Krim
    HeartRhythm case reportsPeer-reviewedCC BY-NC-NDFull textCardiovascular medicineEurope PMC

Cite

BibTeXRIS
BibTeX
@article{marvelde2026serologic,
  title = {{Serologic Testing for Middle East Respiratory Syndrome Coronavirus and SARS-CoV-2 Cross-Reactive Immune Responses, the Netherlands}},
  author = {Merel R. te Marvelde and Anna Z. Mykytyn and Matthijs P. Raadsen and Alexandre H.J. Bouffier and Sivana Baptista Varela and Rory D. de Vries and Corine H. GeurtsvanKessel and Bart L. Haagmans},
  journal = {Emerging Infectious Diseases},
  year = {2026},
  month = oct,
  doi = {10.3201/eid3211.260690},
  url = {https://doi.org/10.3201/eid3211.260690},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Serologic Testing for Middle East Respiratory Syndrome Coronavirus and SARS-CoV-2 Cross-Reactive Immune Responses, the Netherlands
AU  - Merel R. te Marvelde
AU  - Anna Z. Mykytyn
AU  - Matthijs P. Raadsen
AU  - Alexandre H.J. Bouffier
AU  - Sivana Baptista Varela
AU  - Rory D. de Vries
AU  - Corine H. GeurtsvanKessel
AU  - Bart L. Haagmans
PY  - 2026
DA  - 2026/10/30
JO  - Emerging Infectious Diseases
DO  - 10.3201/eid3211.260690
UR  - https://doi.org/10.3201/eid3211.260690
AB  - Cross-reactive SARS-CoV-2–specific antibodies could compromise the specificity of MERS-CoV serology, potentially leading to misclassification of infection history. SARS-CoV-2 exposure induced MERS-CoV antibodies primarily targeting the conserved S2 domain, with occasional neutralizing capacity. Combining MERS-CoV S1 binding with neutralization, however, limited the influence of SARS-CoV-2–induced cross-reactivity on MERS-CoV serology.
SN  - 1080-6040
SN  - 1080-6059
ER  -