Skip to content
DraconiticResearch
Search Sources API
197,768 studies31 sourcesUpdated 15 min ago
Peer-reviewedCC BY-NC-NDClinical case reports

Acute Hemorrhagic Manifestations in a Pregnant Patient With Type 1 von Willebrand Disease: Challenges in Management of Bleeding Disorders During Gestation

  • Jose Luis Rojas‐Oviedo1
  • María Fernanda Leal Walteros1
  • Dauris Lineth Mejía Pérez1
  • Jorge Eliecer Castellanos Corredor2
  • Danna Geraldinne Amaya Sánchez2
  • Ana Sofía Lancheros Ramírez3
  1. 1Universidad Nacional de Colombia
  2. 2Subred Integrada de Servicios de Salud Sur
  3. 3Fundación Universitaria San Martín
Read full textPDFDOICite

Abstract

This case reports a primigravida with Type 1 von Willebrand disease experiencing hematuria and gingival bleeding despite prophylaxis. Although pregnancy raises factor levels, her response was insufficient. Desmopressin successfully controlled mucosal hemorrhage, avoiding antifibrinolytics due to obstructive risk. Management requires multidisciplinary surveillance to tailor peripartum hemostatic interventions.

Related

  1. Interactions between chronic kidney disease and hyperuricemia in children: mechanisms, clinical manifestations and management updates
    Huang Xiaoxia, Liu Yuhua
    Frontiers in pediatricsPeer-reviewedCC BYFull textGeneral medicineEurope PMC
  2. Neglected arboviruses in South America: clinical manifestations and diagnostic challenges
    Milagros Saavedra-Samillán, Sharon Díaz Velásquez, Marcos A Castillo Zuta +3
    Transactions of the Royal Society of Tropical Medicine and HygienePeer-reviewedCC BY 4.0Full textEpidemiology & public healthPMC
  3. Challenges and dilemmas of exercise therapy in the management of osteoporosis: a narrative review
    Jiancheng Yang, Lixin Zhang, Yuhong Zeng
    Frontiers in endocrinologyPeer-reviewedCC BYFull textEndocrinology & metabolismEurope PMC
  4. Pulmonary Epithelioid Trophoblastic Tumor Without Demonstrable Uterine Involvement: A Case Report and Literature Review Highlighting Diagnostic Challenges and Multidisciplinary Management
    Journal of clinical medicinePeer-reviewedCC BYFull textGeneral medicineEurope PMC
  5. Nasopharyngeal Leiomyosarcoma: Diagnostic Challenges and Management of a Rare Head and Neck Sarcoma
    Timothy Morley, Sarah Ridge, Jared Bunevich +2
    CureusPeer-reviewedCC BYFull textGeneral medicineEurope PMC

Cite

BibTeXRIS
BibTeX
@article{rojasoviedo2026acute,
  title = {{Acute Hemorrhagic Manifestations in a Pregnant Patient With Type 1 von Willebrand Disease: Challenges in Management of Bleeding Disorders During Gestation}},
  author = {Jose Luis Rojas‐Oviedo and María Fernanda Leal Walteros and Dauris Lineth Mejía Pérez and Jorge Eliecer Castellanos Corredor and Danna Geraldinne Amaya Sánchez and Ana Sofía Lancheros Ramírez},
  journal = {Clinical case reports},
  year = {2026},
  month = oct,
  doi = {10.1002/ccr3.73728},
  url = {https://europepmc.org/article/PMC/PMC13655370},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Acute Hemorrhagic Manifestations in a Pregnant Patient With Type 1 von Willebrand Disease: Challenges in Management of Bleeding Disorders During Gestation
AU  - Jose Luis Rojas‐Oviedo
AU  - María Fernanda Leal Walteros
AU  - Dauris Lineth Mejía Pérez
AU  - Jorge Eliecer Castellanos Corredor
AU  - Danna Geraldinne Amaya Sánchez
AU  - Ana Sofía Lancheros Ramírez
PY  - 2026
DA  - 2026/10/01
JO  - Clinical case reports
DO  - 10.1002/ccr3.73728
UR  - https://europepmc.org/article/PMC/PMC13655370
AB  - This case reports a primigravida with Type 1 von Willebrand disease experiencing hematuria and gingival bleeding despite prophylaxis. Although pregnancy raises factor levels, her response was insufficient. Desmopressin successfully controlled mucosal hemorrhage, avoiding antifibrinolytics due to obstructive risk. Management requires multidisciplinary surveillance to tailor peripartum hemostatic interventions.
SN  - 2050-0904
ER  -