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Peer-reviewedCC BYGenetics and molecular biology

HVSnp: A manually curated database of human SNPS associated with viral infections.

  1. 1Universidade Federal de São Carlos, Departamento de Genética e Evolução, São Carlos, SP, Brazil.

Abstract

We developed the "HVSnp: Human Viruses SNP-related database, a curated database". HVSnp is exclusive to the human SNPs studied and related to viral diseases, with manually mined and curated information from public SNP databases and scientific articles. We used MySQL (version 8.0) due to the easy management and the Looker Studio online availability. Among the output information, we have SNP identification, reference, alternative, and risk alleles, chromosome, gene, and gene function, summary, among others. In total, HVSnp contains eighteen viral diseases and 2020 records: Adenovirus (17 SNPs), Chikungunya (7), COVID-19 (314), Cytomegalovirus (54), Dengue (62), Epstein-Barr (54), Hepatitis A (3), Hepatitis B (380), Hepatitis C (166), Herpes (8), Human immunodeficiency virus (479), Papillomavirus (87), Influenza (74), Measles (68), Respiratory syncytial virus (50), Sars-CoV (80), West Nile (68), and Zika (49). As one SNP can be associated with more than one virus, the number of unique SNPs is 1691 and 651 genes. HVSnp has supplementary information obtained in articles for the summary elaboration, which contains the most significant results described in the literature about a possible relationship between SNPs and viruses. The database is available at URL: https://lookerstudio.google.com/s/pGUC7m538gQ.

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BibTeX
@article{paganin2026hvsnp,
  title = {{HVSnp: A manually curated database of human SNPS associated with viral infections.}},
  author = {Ana Carolina Laureano Paganin and Caio César de Melo Freire},
  journal = {Genetics and molecular biology},
  year = {2026},
  month = oct,
  doi = {10.1590/1678-4685-gmb-2025-0075},
  url = {https://europepmc.org/article/MED/42896179},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - HVSnp: A manually curated database of human SNPS associated with viral infections.
AU  - Ana Carolina Laureano Paganin
AU  - Caio César de Melo Freire
PY  - 2026
DA  - 2026/10/19
JO  - Genetics and molecular biology
DO  - 10.1590/1678-4685-gmb-2025-0075
UR  - https://europepmc.org/article/MED/42896179
AB  - We developed the "HVSnp: Human Viruses SNP-related database, a curated database". HVSnp is exclusive to the human SNPs studied and related to viral diseases, with manually mined and curated information from public SNP databases and scientific articles. We used MySQL (version 8.0) due to the easy management and the Looker Studio online availability. Among the output information, we have SNP identification, reference, alternative, and risk alleles, chromosome, gene, and gene function, summary, among others. In total, HVSnp contains eighteen viral diseases and 2020 records: Adenovirus (17 SNPs), Chikungunya (7), COVID-19 (314), Cytomegalovirus (54), Dengue (62), Epstein-Barr (54), Hepatitis A (3), Hepatitis B (380), Hepatitis C (166), Herpes (8), Human immunodeficiency virus (479), Papillomavirus (87), Influenza (74), Measles (68), Respiratory syncytial virus (50), Sars-CoV (80), West Nile (68), and Zika (49). As one SNP can be associated with more than one virus, the number of unique SNPs is 1691 and 651 genes. HVSnp has supplementary information obtained in articles for the summary elaboration, which contains the most significant results described in the literature about a possible relationship between SNPs and viruses. The database is available at URL: https://lookerstudio.google.com/s/pGUC7m538gQ.
SN  - 1415-4757
SN  - 1678-4685
ER  -