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Peer-reviewedCC BY 4.0Annals of Thoracic and Cardiovascular Surgery

A Case of Diffuse Pulmonary Ossification Complicated by Obstructive Pneumonia

  • Kazuki Sugata1
  • Yoshitaka Tanaka2
  • Hiroki Katsushima3
  • Yoshio Tsunezuka1
  1. 1Department of General Thoracic Surgery, Saneikai Tsukazaki Hospital, Himeji, Hyogo, Japan
  2. 2Department of General Internal Medicine, Saneikai Hirohata Hospital, Himeji, Hyogo, Japan
  3. 3Department of Pathology, Saneikai Tsukazaki Hospital, Himeji, Hyogo, Japan
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Abstract

Diffuse pulmonary ossification (DPO) is a rare and usually asymptomatic condition characterized by ectopic bone formation in the lungs. A 45-year-old man presented with a low-grade fever, cough, and fatigue. Chest computed tomography revealed a calcified lesion near the left B9 bronchus with bronchial narrowing and distal consolidation, as well as multiple small calcified nodules in the upper and lower lobes of both lungs. Bronchoscopy revealed complete obstruction of the left B9 bronchus. Transbronchial biopsy revealed cartilaginous tissue without malignancy. Despite antibiotic therapy, the symptoms persisted, and malignancy could not be excluded. Subsequently, thoracoscopic surgery was performed. Due to the strong adhesion between the lesion and the bronchus, a left basal segmentectomy was required. Histopathological examination revealed mature trabecular bone with marrow elements, consistent with pulmonary ossification. Although generally benign, pulmonary ossification can cause bronchial obstruction and refractory pneumonia and occasionally require surgical intervention.

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Cite

BibTeXRIS
BibTeX
@article{sugata2026case,
  title = {{A Case of Diffuse Pulmonary Ossification Complicated by Obstructive Pneumonia}},
  author = {Kazuki Sugata and Yoshitaka Tanaka and Hiroki Katsushima and Yoshio Tsunezuka},
  journal = {Annals of Thoracic and Cardiovascular Surgery},
  year = {2026},
  month = oct,
  doi = {10.5761/atcs.cr.26-00096},
  url = {https://doi.org/10.5761/atcs.cr.26-00096},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - A Case of Diffuse Pulmonary Ossification Complicated by Obstructive Pneumonia
AU  - Kazuki Sugata
AU  - Yoshitaka Tanaka
AU  - Hiroki Katsushima
AU  - Yoshio Tsunezuka
PY  - 2026
DA  - 2026/10/24
JO  - Annals of Thoracic and Cardiovascular Surgery
DO  - 10.5761/atcs.cr.26-00096
UR  - https://doi.org/10.5761/atcs.cr.26-00096
AB  - Diffuse pulmonary ossification (DPO) is a rare and usually asymptomatic condition characterized by ectopic bone formation in the lungs. A 45-year-old man presented with a low-grade fever, cough, and fatigue. Chest computed tomography revealed a calcified lesion near the left B9 bronchus with bronchial narrowing and distal consolidation, as well as multiple small calcified nodules in the upper and lower lobes of both lungs. Bronchoscopy revealed complete obstruction of the left B9 bronchus. Transbronchial biopsy revealed cartilaginous tissue without malignancy. Despite antibiotic therapy, the symptoms persisted, and malignancy could not be excluded. Subsequently, thoracoscopic surgery was performed. Due to the strong adhesion between the lesion and the bronchus, a left basal segmentectomy was required. Histopathological examination revealed mature trabecular bone with marrow elements, consistent with pulmonary ossification. Although generally benign, pulmonary ossification can cause bronchial obstruction and refractory pneumonia and occasionally require surgical intervention.
SN  - 1341-1098
SN  - 2186-1005
ER  -