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Peer-reviewedLicence not statedBMJ Open

Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalised Elders (ENHANCE): protocol for a stepped wedge, cluster randomised clinical trial for delirium prevention in older adults

  • Phillip E Vlisides1,2
  • Graciela Mentz1
  • Fan Li3
  • Tamara G Fong4
  • Eva M Schmitt4
  • Amy M McKinney1
  • Karen Donelan5
  • Malaz Boustani6,7,8,9
  • Carrie Bennett10
  • Emily L C Stuckey11,12
  • Elizabeth Chassagne13
  • Shenbagam Dewar14,15
8 more authors
  • Rebecca Trotta16
  • Lyn Weinberg17
  • Roxanne Weiss18
  • Jocelyn Wiggins14
  • Dan Blazer19
  • Mary Cramer20
  • Stephen J Bartels21
  • Sharon K Inouye4
21 affiliations
  1. 1Department of Anesthesiology, Michigan Medicine, Ann Arbor, Michigan, USA
  2. 2Center for Consciousness Science, University of Michigan, Ann Arbor, Michigan, USA
  3. 3Department of Biostatistics, Yale School of Public Helath, New Haven, Connecticut, USA
  4. 4Aging Brain Center, Hinda and Arthur Marcus Institute for Aging Research, Boston, Massachusetts, USA
  5. 5Schneider Institutes for Health Policy and Research, Brandeis University, Waltham, Massachusetts, USA
  6. 6Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
  7. 7Indiana University Center for Aging Research, Indianapolis, Indiana, USA
  8. 8Regenstrief Institute Inc, Indianapolis, Indiana, USA
  9. 9Center for Health Innovation and Implementation Science, Indiana Clinical and Translational Sciences Institute, Indianapolis, Indiana, USA
  10. 10UnityPoint Health - Meriter, Madison, Wisconsin, USA
  11. 11MaineHealth Senior Care, Portland, Maine, USA
  12. 12Department of Family Medicine, Tufts University School of Medicine, Boston, Massachusetts, USA
  13. 13MemioralCare Saddleback Medical Center, Laguna Hills, California, USA
  14. 14Division of Geriatric and Palliative Medicine, Department of Internal Medicine, Michigan Medicine, Ann Arbor, Michigan, USA
  15. 15Geriatric Research Education and Clinical Center, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan, USA
  16. 16Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
  17. 17Division of Geriatrics, Allegheny Health Network, Pittsburgh, Pennsylvania, USA
  18. 18Department of Internal Medicine, The University of Utah School of Medicine, Salt Lake City, Utah, USA
  19. 19Duke University School of Medicine, Durham, North Carolina, USA
  20. 20Family Stakeholder Core, ENHANCE Trial, New York, New York, USA
  21. 21The Mongan Institute, Massachusetts General Hospital, Boston, Massachusetts, USA
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Cite

BibTeXRIS
BibTeX
@article{vlisides2026evaluating,
  title = {{Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalised Elders (ENHANCE): protocol for a stepped wedge, cluster randomised clinical trial for delirium prevention in older adults}},
  author = {Phillip E Vlisides and Graciela Mentz and Fan Li and Tamara G Fong and Eva M Schmitt and Amy M McKinney and Karen Donelan and Malaz Boustani and Carrie Bennett and Emily L C Stuckey and Elizabeth Chassagne and Shenbagam Dewar and Rebecca Trotta and Lyn Weinberg and Roxanne Weiss and Jocelyn Wiggins and Dan Blazer and Mary Cramer and Stephen J Bartels and Sharon K Inouye},
  journal = {BMJ Open},
  year = {2026},
  month = nov,
  doi = {10.1136/bmjopen-2026-123408},
  url = {https://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2026-123408},
}
RIS
TY  - JOUR
TI  - Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalised Elders (ENHANCE): protocol for a stepped wedge, cluster randomised clinical trial for delirium prevention in older adults
AU  - Phillip E Vlisides
AU  - Graciela Mentz
AU  - Fan Li
AU  - Tamara G Fong
AU  - Eva M Schmitt
AU  - Amy M McKinney
AU  - Karen Donelan
AU  - Malaz Boustani
AU  - Carrie Bennett
AU  - Emily L C Stuckey
AU  - Elizabeth Chassagne
AU  - Shenbagam Dewar
AU  - Rebecca Trotta
AU  - Lyn Weinberg
AU  - Roxanne Weiss
AU  - Jocelyn Wiggins
AU  - Dan Blazer
AU  - Mary Cramer
AU  - Stephen J Bartels
AU  - Sharon K Inouye
PY  - 2026
DA  - 2026/11/05
JO  - BMJ Open
DO  - 10.1136/bmjopen-2026-123408
UR  - https://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2026-123408
SN  - 2044-6055
SN  - 2044-6055
ER  -