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Peer-reviewedCC BY-NC-ND 4.0Ecological Complexity

Identifiability analysis and parameter estimation of a chikungunya model in a spatially continuous domain

Abstract

We investigate the identifiability and estimation of parameters of a chikungunya epidemic transmission model. As a novelty, this model incorporates the spatial mobility of humans described as Brownian random motion. Indeed, it is a factor that has influenced the re-emergence of several epidemic diseases. The displacement of mosquitoes is omitted since it is limited to a few meters. This model couples a mosquito dynamics model and a transmission virus model between humans and mosquitoes populations. The mosquito larvae and the human population are supposed to be observed. The complete model is then composed of a reaction–diffusion system coupled with ordinary differential equations (ODEs). The diffusion is assumed to be local. For such a model, the identifiability analysis is studied at first to ensure that the parameters can be uniquely identified. From the identifiability study, we propose a numerical procedure for obtaining a first estimate of the parameters of the transmission virus model without any knowledge of them.

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BibTeX
@article{zhu2026identifiability,
  title = {{Identifiability analysis and parameter estimation of a chikungunya model in a spatially continuous domain}},
  author = {Shousheng Zhu and Nathalie Verdière and Lilianne Denis-Vidal and Djalil Kateb},
  journal = {Ecological Complexity},
  year = {2026},
  month = sep,
  doi = {10.1016/j.ecocom.2017.12.004},
  url = {https://hal.science/hal-02305310v1},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Identifiability analysis and parameter estimation of a chikungunya model in a spatially continuous domain
AU  - Shousheng Zhu
AU  - Nathalie Verdière
AU  - Lilianne Denis-Vidal
AU  - Djalil Kateb
PY  - 2026
DA  - 2026/09/09
JO  - Ecological Complexity
DO  - 10.1016/j.ecocom.2017.12.004
UR  - https://hal.science/hal-02305310v1
AB  - We investigate the identifiability and estimation of parameters of a chikungunya epidemic transmission model. As a novelty, this model incorporates the spatial mobility of humans described as Brownian random motion. Indeed, it is a factor that has influenced the re-emergence of several epidemic diseases. The displacement of mosquitoes is omitted since it is limited to a few meters. This model couples a mosquito dynamics model and a transmission virus model between humans and mosquitoes populations. The mosquito larvae and the human population are supposed to be observed. The complete model is then composed of a reaction–diffusion system coupled with ordinary differential equations (ODEs). The diffusion is assumed to be local. For such a model, the identifiability analysis is studied at first to ensure that the parameters can be uniquely identified. From the identifiability study, we propose a numerical procedure for obtaining a first estimate of the parameters of the transmission virus model without any knowledge of them.
SN  - 1476-945X
ER  -