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Peer-reviewedCC BY-NC-ND 4.0The Australasian Journal of Dermatology

Telangiectasia in Systemic Sclerosis Is a Marker of Increased Disease Morbidity and Mortality: Analyses From the Australian Scleroderma Cohort Study

  • Vivien Wai Yun Lai1
  • Dylan Hansen2
  • Maryam Tabesh3
  • Jessica Fairley2,3
  • Laura Ross2,3
  • Nava Ferdowsi3
  • Gene‐Siew Ngian4,5
  • Diane Apostolopoulos4
  • Joanne Sahhar4
  • Lauren V. Host6
  • Jennifer Walker7
  • Gabor Major8,9
4 more authors
  • Susanna Proudman10,11
  • Wendy Stevens2,3
  • Mandana Nikpour2,3,12,13
  • Amanda M. Saracino2,14,15
15 affiliations
  1. 1Department of Dermatology The Royal Melbourne Hospital Parkville Victoria Australia
  2. 2The University of Melbourne, St. Vincent's Hospital, Melbourne Melbourne Victoria Australia
  3. 3Department of Rheumatology St Vincent's Hospital, Melbourne Melbourne Victoria Australia
  4. 4Department of Rheumatology Monash Medical Centre Melbourne Victoria Australia
  5. 5Department of Medicine Monash University Melbourne Victoria Australia
  6. 6Department of Rheumatology Fiona Stanley Hospital Perth Western Australia Australia
  7. 7Flinders University of South Australia, Flinders Medical Centre Bedford Park South Australia Australia
  8. 8Department of Rheumatology, Bone & Joint Institute Royal Newcastle Centre, John Hunter Hospital Newcastle New South Wales Australia
  9. 9Faculty of Medicine University of Newcastle Callaghan New South Wales Australia
  10. 10Rheumatology Unit Royal Adelaide Hospital Adelaide South Australia Australia
  11. 11Discipline of Medicine University of Adelaide Adelaide South Australia Australia
  12. 12School of Public Health the University of Sydney Sydney Australia
  13. 13Department of Rheumatology Royal Prince Alfred Hospital Sydney Australia
  14. 14Department of Dermatology St Vincent's Hospital, Melbourne Melbourne Victoria Australia
  15. 15Centre for Rheumatology and Connective Tissue Diseases, Division of Medicine University College London London UK
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Abstract

This Australian retrospective cohort analysis of 1977 patients investigates and expands on correlates of telangiectasia in systemic sclerosis to determine whether this cutaneous sign is a potential surrogate marker for disease progression and prognosis. We found that pulmonary arterial hypertension and digital ulcers were significant correlates of telangiectasia, which was also an independent risk factor for mortality. Careful monitoring of telangiectasia may provide an indicator for more severe vasculopathy, with increased morbidity and mortality in systemic sclerosis.

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Cite

BibTeXRIS
BibTeX
@article{lai2026telangiectasia,
  title = {{Telangiectasia in Systemic Sclerosis Is a Marker of Increased Disease Morbidity and Mortality: Analyses From the Australian Scleroderma Cohort Study}},
  author = {Vivien Wai Yun Lai and Dylan Hansen and Maryam Tabesh and Jessica Fairley and Laura Ross and Nava Ferdowsi and Gene‐Siew Ngian and Diane Apostolopoulos and Joanne Sahhar and Lauren V. Host and Jennifer Walker and Gabor Major and Susanna Proudman and Wendy Stevens and Mandana Nikpour and Amanda M. Saracino},
  journal = {The Australasian Journal of Dermatology},
  year = {2026},
  month = jul,
  doi = {10.1111/ajd.70179},
  url = {https://doi.org/10.1111/ajd.70179},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Telangiectasia in Systemic Sclerosis Is a Marker of Increased Disease Morbidity and Mortality: Analyses From the Australian Scleroderma Cohort Study
AU  - Vivien Wai Yun Lai
AU  - Dylan Hansen
AU  - Maryam Tabesh
AU  - Jessica Fairley
AU  - Laura Ross
AU  - Nava Ferdowsi
AU  - Gene‐Siew Ngian
AU  - Diane Apostolopoulos
AU  - Joanne Sahhar
AU  - Lauren V. Host
AU  - Jennifer Walker
AU  - Gabor Major
AU  - Susanna Proudman
AU  - Wendy Stevens
AU  - Mandana Nikpour
AU  - Amanda M. Saracino
PY  - 2026
DA  - 2026/07/06
JO  - The Australasian Journal of Dermatology
DO  - 10.1111/ajd.70179
UR  - https://doi.org/10.1111/ajd.70179
AB  - This Australian retrospective cohort analysis of 1977 patients investigates and expands on correlates of telangiectasia in systemic sclerosis to determine whether this cutaneous sign is a potential surrogate marker for disease progression and prognosis. We found that pulmonary arterial hypertension and digital ulcers were significant correlates of telangiectasia, which was also an independent risk factor for mortality. Careful monitoring of telangiectasia may provide an indicator for more severe vasculopathy, with increased morbidity and mortality in systemic sclerosis.
SN  - 0004-8380
SN  - 1440-0960
ER  -