Peer-reviewedCC BYEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Rapid inter-regional and cross-border dissemination of carbapenemase-producing Klebsiella pneumoniae ST6668, European Union, April 2022 to August 2026.
14 affiliations
- 1National Reference Laboratory for Antimicrobial Resistance, Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy
- 2European Centre for Disease Prevention and Control, Solna, Sweden
- 3Core Facilities Technical-Scientific Service, Istituto Superiore di Sanità, Rome, Italy
- 4National Reference Laboratory for Antimicrobial Resistance, Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark
- 5European Union Reference Laboratory for Public Health on Antimicrobial Resistance in Bacteria (EURL-PH-AMR), Copenhagen, Denmark
- 6French National Reference Center for Antibiotic Resistance, Le Kremlin-Bicêtre, France
- 7Team 'Resist' UMR1184 'Immunology of Viral, Auto-Immune, Hematological and Bacterial Diseases (IMVA-HB)', INSERM, Université Paris-Saclay, CEA, LabEx LERMIT, Le Kremlin-Bicêtre Cedex, France
- 8Department of Bacteriology-Hygiene, Bicêtre Hospital, Assistance Publique-Hôpitaux de Paris, Le Kremlin-Bicêtre, France
- 9Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany
- 10German National Reference Centre for Multidrug-resistant Gram-negative Bacteria, Department of Medical Microbiology, Ruhr-University Bochum, Bochum, Germany
- 11Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands
- 12Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
- 13National Institute for Infectious Disease “Prof. Dr. Matei Balş”, Bucharest, Romania
- 14The members of the Italian CRE25 survey working group for Klebsiella pneumoniae ST6668 are listed under Collaborators and at the end of the article.
Abstract
Preliminary analysis of genomic surveillance data from the European Antimicrobial Resistance Gene Surveillance Network detected the spread of the emerging carbapenemase-producing Klebsiella pneumoniae sequence type ST6668 in 19 NUTS-2 regions in Italy (8 regions) and five other European Union (EU) countries (11 regions) in the period April 2022 to August 2026. These findings demonstrate the vulnerability of EU healthcare facilities to the rapid spread of K. pneumoniae high-risk lineages from uncontrolled local outbreaks via national and cross-border patient mobility.
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BibTeX
@article{errico2026rapid,
title = {{Rapid inter-regional and cross-border dissemination of carbapenemase-producing Klebsiella pneumoniae ST6668, European Union, April 2022 to August 2026.}},
author = {Giulia Errico and Marius Linkevicius and Alessandra Lo Sciuto and Cristiana Barbati and Sara Giancristofaro and Manuela Marra and Valentina Libri and Maria Del Grosso and Anette M Hammerum and Louise Roer and Rémy A Bonnin and Laurent Dortet and Felix Reichert and Lisa-Marie Höfken and Antoni PA Hendrickx and Dragos Florea and Daniela Talapan and Erik Alm and Olov Svartström and Priyanka Nannapaneni and Anke Kohlenberg and Monica Monaco and the Italian CRE25 survey working group for Klebsiella pneumoniae ST6668 and Collaborators and Claudio Giacomazzi and Marisa Accogli and Maria Chironna and Floriana Gona and Maddalena Calvo and Stefania Stefani and Francesca Greco and Chiara Vismara and Teresa Lopizzo and Sofia Chiatamone Ranieri and Annarita Mazzariol and Luciano Castiello},
journal = {Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin},
year = {2026},
month = oct,
doi = {10.2807/1560-7917.es.2026.31.43.2600861},
url = {https://europepmc.org/article/MED/42960468},
note = {CC BY},
}
RIS
TY - JOUR
TI - Rapid inter-regional and cross-border dissemination of carbapenemase-producing Klebsiella pneumoniae ST6668, European Union, April 2022 to August 2026.
AU - Giulia Errico
AU - Marius Linkevicius
AU - Alessandra Lo Sciuto
AU - Cristiana Barbati
AU - Sara Giancristofaro
AU - Manuela Marra
AU - Valentina Libri
AU - Maria Del Grosso
AU - Anette M Hammerum
AU - Louise Roer
AU - Rémy A Bonnin
AU - Laurent Dortet
AU - Felix Reichert
AU - Lisa-Marie Höfken
AU - Antoni PA Hendrickx
AU - Dragos Florea
AU - Daniela Talapan
AU - Erik Alm
AU - Olov Svartström
AU - Priyanka Nannapaneni
AU - Anke Kohlenberg
AU - Monica Monaco
AU - the Italian CRE25 survey working group for Klebsiella pneumoniae ST6668
AU - Collaborators
AU - Claudio Giacomazzi
AU - Marisa Accogli
AU - Maria Chironna
AU - Floriana Gona
AU - Maddalena Calvo
AU - Stefania Stefani
AU - Francesca Greco
AU - Chiara Vismara
AU - Teresa Lopizzo
AU - Sofia Chiatamone Ranieri
AU - Annarita Mazzariol
AU - Luciano Castiello
PY - 2026
DA - 2026/10/01
JO - Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
DO - 10.2807/1560-7917.es.2026.31.43.2600861
UR - https://europepmc.org/article/MED/42960468
AB - Preliminary analysis of genomic surveillance data from the European Antimicrobial Resistance Gene Surveillance Network detected the spread of the emerging carbapenemase-producing Klebsiella pneumoniae sequence type ST6668 in 19 NUTS-2 regions in Italy (8 regions) and five other European Union (EU) countries (11 regions) in the period April 2022 to August 2026. These findings demonstrate the vulnerability of EU healthcare facilities to the rapid spread of K. pneumoniae high-risk lineages from uncontrolled local outbreaks via national and cross-border patient mobility.
SN - 1025-496X
SN - 1560-7917
ER -