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PreprintCC BYbioRxiv

Short-read whole-genome sequencing identifies the Tg(Tal1-cre/ERT)42-056Jrg transgene insertion site on mouse chromosome 4

  • X. Wu
  • M. C. Bagish
  • P. Sanchez Vela
  • A. G. Goglia
  • R. L. Levine1
  1. 1Memorial Sloan Kettering Cancer Center
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Abstract

Tg(Tal1-cre/ERT)42-056Jrg, also known as HSC-Scl-CreERT, is a well-used transgenic allele that enables genetic manipulation in mouse hematopoietic cells. Using short-read whole-genome sequencing, we identified the transgene insertion site on chromosome 4 approximately 6 kb upstream of Echdc2.

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Cite

BibTeXRIS
BibTeX
@misc{wu2026shortread,
  title = {{Short-read whole-genome sequencing identifies the Tg(Tal1-cre/ERT)42-056Jrg transgene insertion site on mouse chromosome 4}},
  author = {X. Wu and M. C. Bagish and P. Sanchez Vela and A. G. Goglia and R. L. Levine},
  howpublished = {bioRxiv},
  year = {2026},
  month = nov,
  doi = {10.64898/2026.11.04.764251},
  url = {https://www.biorxiv.org/content/10.64898/2026.11.04.764251v1},
  note = {CC BY},
}
RIS
TY  - UNPB
TI  - Short-read whole-genome sequencing identifies the Tg(Tal1-cre/ERT)42-056Jrg transgene insertion site on mouse chromosome 4
AU  - X. Wu
AU  - M. C. Bagish
AU  - P. Sanchez Vela
AU  - A. G. Goglia
AU  - R. L. Levine
PY  - 2026
DA  - 2026/11/04
PB  - bioRxiv
DO  - 10.64898/2026.11.04.764251
UR  - https://www.biorxiv.org/content/10.64898/2026.11.04.764251v1
AB  - Tg(Tal1-cre/ERT)42-056Jrg, also known as HSC-Scl-CreERT, is a well-used transgenic allele that enables genetic manipulation in mouse hematopoietic cells. Using short-read whole-genome sequencing, we identified the transgene insertion site on chromosome 4 approximately 6 kb upstream of Echdc2.
ER  -