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Peer-reviewedCC BYFrontiers in medicine

Research progress and trends of gut microbiota and lung injury: a bibliometric and visualization analysis based on two databases (2015–2026)

  • Xinru Wu1
  • Tiancheng Yu2
  • Shuai Hu3
  • Tianyi Zhang1
  1. 1Kunshan Integrated TCM and Western Medicine Hospital , ,
  2. 2School of Physical Education, Nanjing Tech University, Nanjing, China
  3. 3Sports and Health Collaborative Innovation Center for Fitness Promotion, Jiangsu Normal University , ,
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Abstract

Background

Gut microbiota has emerged as an important regulator of lung injury, but the field's research structure, hotspots and emerging directions remain unclear. This study mapped the development and knowledge landscape of gut microbiota and lung injury research.Methods

Publications indexed in the Web of Science Core Collection (WoSCC) and Scopus from 2015 to May 2026 were analyzed using VOSviewer, CiteSpace and Bibliometrix.Results

Publication output increased markedly, particularly after 2019, with China and Fudan University leading national and institutional contributions, respectively. Frontiers in Immunology was a major publication and citation hub. Keyword patterns highlighted inflammation, the gut-lung axis, immune regulation, mouse models and sepsis.Conclusion

Major research themes included microbiota-mediated regulation of pulmonary immunity, the protective effects of short-chain fatty acids (SCFAs), and microbiota-targeted interventions involving probiotics and traditional Chinese medicine (TCM). The field remains dominated by mechanistic and preclinical studies, underscoring the need for standardized methods and clinical validation.

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Cite

BibTeXRIS
BibTeX
@article{wu2026research,
  title = {{Research progress and trends of gut microbiota and lung injury: a bibliometric and visualization analysis based on two databases (2015–2026)}},
  author = {Xinru Wu and Tiancheng Yu and Shuai Hu and Tianyi Zhang},
  journal = {Frontiers in medicine},
  year = {2026},
  month = oct,
  doi = {10.3389/fmed.2026.1902880},
  url = {https://europepmc.org/article/PMC/PMC13716728},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Research progress and trends of gut microbiota and lung injury: a bibliometric and visualization analysis based on two databases (2015–2026)
AU  - Xinru Wu
AU  - Tiancheng Yu
AU  - Shuai Hu
AU  - Tianyi Zhang
PY  - 2026
DA  - 2026/10/15
JO  - Frontiers in medicine
DO  - 10.3389/fmed.2026.1902880
UR  - https://europepmc.org/article/PMC/PMC13716728
AB  - Background  Gut microbiota has emerged as an important regulator of lung injury, but the field's research structure, hotspots and emerging directions remain unclear. This study mapped the development and knowledge landscape of gut microbiota and lung injury research.Methods  Publications indexed in the Web of Science Core Collection (WoSCC) and Scopus from 2015 to May 2026 were analyzed using VOSviewer, CiteSpace and Bibliometrix.Results  Publication output increased markedly, particularly after 2019, with China and Fudan University leading national and institutional contributions, respectively. Frontiers in Immunology was a major publication and citation hub. Keyword patterns highlighted inflammation, the gut-lung axis, immune regulation, mouse models and sepsis.Conclusion  Major research themes included microbiota-mediated regulation of pulmonary immunity, the protective effects of short-chain fatty acids (SCFAs), and microbiota-targeted interventions involving probiotics and traditional Chinese medicine (TCM). The field remains dominated by mechanistic and preclinical studies, underscoring the need for standardized methods and clinical validation.
SN  - 2296-858X
ER  -