Peer-reviewedCC BY-NC-NDCirculation Journal
Residual Pulmonary Hypertension After Transcatheter Edge-to-Edge Repair in Patients With Secondary Mitral Regurgitation
Abstract
BACKGROUND: The effect of residual pulmonary hypertension (PH) on clinical outcomes in patients with secondary mitral regurgitation (MR) after transcatheter edge-to-edge repair (TEER) remains unexplored. METHODS AND RESULTS: We analyzed 62 patients with secondary MR who underwent TEER. In 32 (51.6%) patients with residual PH after TEER, adverse clinical events were observed more frequently compared with those without residual PH. Multivariate analysis confirmed residual PH as an independent predictor of all-cause death or hospitalization for heart failure. CONCLUSIONS: In patients with secondary MR, residual PH after TEER is an independent predictor of adverse clinical outcomes.
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BibTeX
@article{tsubata2026residual,
title = {{Residual Pulmonary Hypertension After Transcatheter Edge-to-Edge Repair in Patients With Secondary Mitral Regurgitation}},
author = {Hideo Tsubata and Naohiko Nakanishi and Kazuaki Takamatsu and Masaki Yashige and Tomotaka Fujimoto and Yuki Matsubara and Hideki Kimura and Tomoyuki Nagai and Michiyo Yamano and Tetsuhiro Yamano and Kan Zen and Satoaki Matoba},
journal = {Circulation Journal},
year = {2026},
month = aug,
doi = {10.1253/circj.cj-25-0922},
url = {https://www.jstage.jst.go.jp/article/circj/90/9/90_CJ-25-0922/_article},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Residual Pulmonary Hypertension After Transcatheter Edge-to-Edge Repair in Patients With Secondary Mitral Regurgitation
AU - Hideo Tsubata
AU - Naohiko Nakanishi
AU - Kazuaki Takamatsu
AU - Masaki Yashige
AU - Tomotaka Fujimoto
AU - Yuki Matsubara
AU - Hideki Kimura
AU - Tomoyuki Nagai
AU - Michiyo Yamano
AU - Tetsuhiro Yamano
AU - Kan Zen
AU - Satoaki Matoba
PY - 2026
DA - 2026/08/25
JO - Circulation Journal
DO - 10.1253/circj.cj-25-0922
UR - https://www.jstage.jst.go.jp/article/circj/90/9/90_CJ-25-0922/_article
AB - BACKGROUND: The effect of residual pulmonary hypertension (PH) on clinical outcomes in patients with secondary mitral regurgitation (MR) after transcatheter edge-to-edge repair (TEER) remains unexplored. METHODS AND RESULTS: We analyzed 62 patients with secondary MR who underwent TEER. In 32 (51.6%) patients with residual PH after TEER, adverse clinical events were observed more frequently compared with those without residual PH. Multivariate analysis confirmed residual PH as an independent predictor of all-cause death or hospitalization for heart failure. CONCLUSIONS: In patients with secondary MR, residual PH after TEER is an independent predictor of adverse clinical outcomes.
SN - 1347-4820
SN - 1346-9843
ER -