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Peer-reviewedCC BYArquivos de gastroenterologia

NUTRITIONAL OUTCOMES AFTER ONE ANASTOMOSIS GASTRIC BYPASS VERSUS ROUX-EN-Y GASTRIC BYPASS: A ONE-YEAR COMPARATIVE STUDY Desfechos nutricionais após derivação gástrica em Y-de-Roux versus derivação gastrojejunal com anastomose única: estudo comparativo de um ano

  • Priscilla SAMPAIO1
  • Denis PAJECKI2
  • Marco Aurelio SANTO2
  • Maria Carolina Gonçalves DIAS1
  • Marco Aurelio SANTO2
  1. 1Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas HCFMUSP, Divisão de Nutrição e Dietética, São Paulo, SP, Brasil.
  2. 2Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas HCFMUSP, Departamento de Gastroenterologia, Disciplina de Cirurgia do Aparelho Digestivo e Coloproctologia, Unidade de Cirurgia Bariátrica e Metabólica, São Paulo, SP, Brasil.
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Abstract

Background: : Metabolic and bariatric surgery is an effective obesity treatment. One anastomosis gastric bypass (OAGB) has emerged as an alternative to Roux-en-Y gastric bypass (RYGB); however, evidence regarding its postoperative nutritional outcomes remains limited. Objective: To compare food tolerance, gastrointestinal symptoms, and nutritional status between OAGB and RYGB one year after surgery.

Methods: : This retrospective, observational, comparative study included 46 patients (16 OAGB and 30 RYGB). Weight loss, laboratory parameters, dietary intake, food tolerance, and gastrointestinal symptoms were evaluated one year postoperatively. Linear regression models were adjusted for relevant confounding variables, including age, sex, and baseline values when appropriate.

Results: : The percentage of total weight loss (29.55% vs 26.32%) and excess weight loss (63.36% vs 58.29%) were similar between RYGB and OAGB groups (P>0.05). A high prevalence of vitamin D deficiency was observed in both groups (RYGB: 82% vs. OAGB: 92%). Elevated parathyroid hormone levels were more frequent in the OAGB group (75% vs 50%), although the difference was not statistically significant. OAGB patients showed numerically lower serum iron and reduced transferrin saturation; however, none of the patients developed anemia. Mean protein intake met the recommended levels in both groups, whereas fiber intake was below the minimum recommended level. OAGB patients presented significantly lower gastrointestinal symptom scores for diarrhea, indigestion, and total score (P<0.05). Food tolerance was satisfactory and similar between groups.

Conclusion: : Under structured multidisciplinary follow-up, OAGB and RYGB demonstrated comparable nutritional outcomes. OAGB appears to be a nutritionally safe alternative at one year of follow-up, with the need for ongoing monitoring of iron and vitamin D status.

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Cite

BibTeXRIS
BibTeX
@article{sampaio2026nutritional,
  title = {{NUTRITIONAL OUTCOMES AFTER ONE ANASTOMOSIS GASTRIC BYPASS VERSUS ROUX-EN-Y GASTRIC BYPASS: A ONE-YEAR COMPARATIVE STUDY Desfechos nutricionais após derivação gástrica em Y-de-Roux versus derivação gastrojejunal com anastomose única: estudo comparativo de um ano}},
  author = {Priscilla SAMPAIO and Denis PAJECKI and Marco Aurelio SANTO and Maria Carolina Gonçalves DIAS and Marco Aurelio SANTO},
  journal = {Arquivos de gastroenterologia},
  year = {2026},
  month = oct,
  doi = {10.1590/s0004-2803.24612026-040},
  url = {https://europepmc.org/article/PMC/PMC13722410},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - NUTRITIONAL OUTCOMES AFTER ONE ANASTOMOSIS GASTRIC BYPASS VERSUS ROUX-EN-Y GASTRIC BYPASS: A ONE-YEAR COMPARATIVE STUDY Desfechos nutricionais após derivação gástrica em Y-de-Roux versus derivação gastrojejunal com anastomose única: estudo comparativo de um ano
AU  - Priscilla SAMPAIO
AU  - Denis PAJECKI
AU  - Marco Aurelio SANTO
AU  - Maria Carolina Gonçalves DIAS
AU  - Marco Aurelio SANTO
PY  - 2026
DA  - 2026/10/30
JO  - Arquivos de gastroenterologia
DO  - 10.1590/s0004-2803.24612026-040
UR  - https://europepmc.org/article/PMC/PMC13722410
AB  - Background: : Metabolic and bariatric surgery is an effective obesity treatment. One anastomosis gastric bypass (OAGB) has emerged as an alternative to Roux-en-Y gastric bypass (RYGB); however, evidence regarding its postoperative nutritional outcomes remains limited. Objective: To compare food tolerance, gastrointestinal symptoms, and nutritional status between OAGB and RYGB one year after surgery.  Methods: : This retrospective, observational, comparative study included 46 patients (16 OAGB and 30 RYGB). Weight loss, laboratory parameters, dietary intake, food tolerance, and gastrointestinal symptoms were evaluated one year postoperatively. Linear regression models were adjusted for relevant confounding variables, including age, sex, and baseline values when appropriate.  Results: : The percentage of total weight loss (29.55% vs 26.32%) and excess weight loss (63.36% vs 58.29%) were similar between RYGB and OAGB groups (P>0.05). A high prevalence of vitamin D deficiency was observed in both groups (RYGB: 82% vs. OAGB: 92%). Elevated parathyroid hormone levels were more frequent in the OAGB group (75% vs 50%), although the difference was not statistically significant. OAGB patients showed numerically lower serum iron and reduced transferrin saturation; however, none of the patients developed anemia. Mean protein intake met the recommended levels in both groups, whereas fiber intake was below the minimum recommended level. OAGB patients presented significantly lower gastrointestinal symptom scores for diarrhea, indigestion, and total score (P<0.05). Food tolerance was satisfactory and similar between groups.  Conclusion: : Under structured multidisciplinary follow-up, OAGB and RYGB demonstrated comparable nutritional outcomes. OAGB appears to be a nutritionally safe alternative at one year of follow-up, with the need for ongoing monitoring of iron and vitamin D status.
SN  - 0004-2803
SN  - 1678-4219
ER  -