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Peer-reviewedCC BY 4.0Journal of Clinical Medicine

Frontiers in the Risk Stratification and Prevention of Sudden Cardiac Arrest and Death in Athletes

  1. 1Department of Cardiovascular Medicine, The University of Kansas Medical Center, Kansas City, KS 66160, USA
  2. 2Department of Family Medicine, The University of Kansas Medical Center, Kansas City, KS 66160, USA

Abstract

Background: Sudden cardiac arrest (SCA) and sudden cardiac death (SCD) remain the leading causes of exercise-related mortality in athletes. Research in recent years has produced substantial advances in the understanding of athlete-specific risk, the etiologic spectrum of SCA/SCD, and the tools available for screening and risk stratification. Methods: We performed a narrative review of the literature identified through PubMed/MEDLINE searches of related terms, supplemented by targeted searches and reference checking. Summary of the Review: In this narrative review, we synthesize updated evidence on the epidemiology, etiologies, screening, and emerging technologies relevant to SCA/SCD in athletes. Conclusions: Contemporary evaluation of SCA/SCD risk in athletes relies on multimodal, individualized assessment with longitudinal surveillance and shared decision-making. Emerging computational tools may further refine risk prediction, but current evidence remains limited.

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BibTeX
@article{cushing2026frontiers,
  title = {{Frontiers in the Risk Stratification and Prevention of Sudden Cardiac Arrest and Death in Athletes}},
  author = {Jacob Cushing and Luke Hamar and John Fritzlen},
  journal = {Journal of Clinical Medicine},
  year = {2026},
  month = oct,
  doi = {10.3390/jcm15207920},
  url = {https://www.mdpi.com/2077-0383/15/20/7920},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Frontiers in the Risk Stratification and Prevention of Sudden Cardiac Arrest and Death in Athletes
AU  - Jacob Cushing
AU  - Luke Hamar
AU  - John Fritzlen
PY  - 2026
DA  - 2026/10/01
JO  - Journal of Clinical Medicine
DO  - 10.3390/jcm15207920
UR  - https://www.mdpi.com/2077-0383/15/20/7920
AB  - Background: Sudden cardiac arrest (SCA) and sudden cardiac death (SCD) remain the leading causes of exercise-related mortality in athletes. Research in recent years has produced substantial advances in the understanding of athlete-specific risk, the etiologic spectrum of SCA/SCD, and the tools available for screening and risk stratification. Methods: We performed a narrative review of the literature identified through PubMed/MEDLINE searches of related terms, supplemented by targeted searches and reference checking. Summary of the Review: In this narrative review, we synthesize updated evidence on the epidemiology, etiologies, screening, and emerging technologies relevant to SCA/SCD in athletes. Conclusions: Contemporary evaluation of SCA/SCD risk in athletes relies on multimodal, individualized assessment with longitudinal surveillance and shared decision-making. Emerging computational tools may further refine risk prediction, but current evidence remains limited.
SN  - 2077-0383
ER  -