Unilateral Angle Closure as the Initial Presentation of Multiple Myeloma Metastasis.
- 1Ho Chi Minh City Eye Hospital, Xuan Hoa Ward, Ho Chi Minh City, Vietnam.
- 2Pham Ngoc Thach University of Medicine, Hoa Hung Ward, Ho Chi Minh City, Vietnam.
Abstract
Purpose
Ocular manifestations of multiple myeloma (MM) are rare but may affect all tissues of the eye. This report describes a patient with recurrent MM initially presenting with ocular hypertension due to angle closure, revealing extensive ocular, orbital, and systemic metastatic disease.Case report
A 54-year-old female patient with previously treated MM presented with left eye pain, blurred vision, and an intraocular pressure of 38 mmHg. Examination revealed proptosis, restricted upward gaze, conjunctival injection with two salmon-patch lesions, and complete angle closure. Further findings included multiple ciliary body cysts, a massive choroidal mass, and retinal/choroidal detachments. She had pancytopenia. Magnetic resonance imaging confirmed recurrent MM with superior rectus muscle and spine infiltrations, and a large prevertebral lymph node mass. The patient responded well to antiglaucoma medications and was referred to her oncologist.Conclusion
MM can involve various ophthalmic structures. Patients with MM require regular examinations for early detection of ocular metastasis.
Related
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BibTeX
@article{nguyen2026unilateral,
title = {{Unilateral Angle Closure as the Initial Presentation of Multiple Myeloma Metastasis.}},
author = {Thao Huong Nguyen and Truong Dang Minh Pham and Thanh Nghiep Trang and Ngoc Phuong Vy Ly and Hong Y Huynh},
journal = {Journal of ophthalmic \& vision research},
year = {2026},
month = oct,
doi = {10.18502/jovr.v21.19965},
url = {https://europepmc.org/article/MED/43011673},
note = {CC BY},
}
RIS
TY - JOUR
TI - Unilateral Angle Closure as the Initial Presentation of Multiple Myeloma Metastasis.
AU - Thao Huong Nguyen
AU - Truong Dang Minh Pham
AU - Thanh Nghiep Trang
AU - Ngoc Phuong Vy Ly
AU - Hong Y Huynh
PY - 2026
DA - 2026/10/22
JO - Journal of ophthalmic & vision research
DO - 10.18502/jovr.v21.19965
UR - https://europepmc.org/article/MED/43011673
AB - Purpose Ocular manifestations of multiple myeloma (MM) are rare but may affect all tissues of the eye. This report describes a patient with recurrent MM initially presenting with ocular hypertension due to angle closure, revealing extensive ocular, orbital, and systemic metastatic disease.Case report A 54-year-old female patient with previously treated MM presented with left eye pain, blurred vision, and an intraocular pressure of 38 mmHg. Examination revealed proptosis, restricted upward gaze, conjunctival injection with two salmon-patch lesions, and complete angle closure. Further findings included multiple ciliary body cysts, a massive choroidal mass, and retinal/choroidal detachments. She had pancytopenia. Magnetic resonance imaging confirmed recurrent MM with superior rectus muscle and spine infiltrations, and a large prevertebral lymph node mass. The patient responded well to antiglaucoma medications and was referred to her oncologist.Conclusion MM can involve various ophthalmic structures. Patients with MM require regular examinations for early detection of ocular metastasis.
SN - 2008-2010
SN - 2008-322X
ER -