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Peer-reviewedCC BYThe Egyptian Journal of Otolaryngology

Diffusion-weighted magnetic resonance imaging and immunohistochemistry in Epstein-Barr virus-positive diffuse large B-cell lymphoma of the maxilla: a rare case report

  • Yoriaki Kanri1
  • Yuko Watarai2
  • Ryo Mizuhashi3
  • Ichiro Ogura4
  • Yasuo Okada1
4 affiliations
  1. 1Department of Pathology, The Nippon Dental University School of Life Dentistry at Niigata
  2. 2Department of Removable Prosthodontics, The Nippon Dental University School of Life Dentistry at Niigata
  3. 3Comprehensive Dental Care, The Nippon Dental University Niigata Hospital
  4. 4Department of Oral and Maxillofacial Radiology, The Nippon Dental University School of Life Dentistry at Niigata
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Abstract

Background Epstein-Barr virus-positive diffuse large B-cell lymphoma of the maxilla is rare. Case presentation A 90-year-old male patient presented to our hospital with numbness and swelling in the right maxillary region extending to the lip. He underwent computed tomography and magnetic resonance imaging for pretreatment. Diffusion-weighted magnetic resonance imaging of the lesions revealed a high-signal intensity area, and the apparent diffusion coefficient value of the lesion was 0.61 × 10− 3 mm2s− 1. A partial biopsy of the maxillary region was performed. A diagnosis of Epstein-Barr virus-positive diffuse large B-cell lymphoma was made on the basis of immunohistochemical staining. The patient was transferred to another hospital for treatment. Conclusion This case demonstrates that diffusion-weighted magnetic resonance imaging and immunohistochemistry may be essential for diagnosing Epstein-Barr virus-positive diffuse large B-cell lymphoma.

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Cite

BibTeXRIS
BibTeX
@article{kanri2026diffusionweighted,
  title = {{Diffusion-weighted magnetic resonance imaging and immunohistochemistry in Epstein-Barr virus-positive diffuse large B-cell lymphoma of the maxilla: a rare case report}},
  author = {Yoriaki Kanri and Yuko Watarai and Ryo Mizuhashi and Ichiro Ogura and Yasuo Okada},
  journal = {The Egyptian Journal of Otolaryngology},
  year = {2026},
  month = oct,
  doi = {10.1186/s43163-026-01244-8},
  url = {https://doi.org/10.1186/s43163-026-01244-8},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Diffusion-weighted magnetic resonance imaging and immunohistochemistry in Epstein-Barr virus-positive diffuse large B-cell lymphoma of the maxilla: a rare case report
AU  - Yoriaki Kanri
AU  - Yuko Watarai
AU  - Ryo Mizuhashi
AU  - Ichiro Ogura
AU  - Yasuo Okada
PY  - 2026
DA  - 2026/10/25
JO  - The Egyptian Journal of Otolaryngology
DO  - 10.1186/s43163-026-01244-8
UR  - https://doi.org/10.1186/s43163-026-01244-8
AB  - Background Epstein-Barr virus-positive diffuse large B-cell lymphoma of the maxilla is rare. Case presentation A 90-year-old male patient presented to our hospital with numbness and swelling in the right maxillary region extending to the lip. He underwent computed tomography and magnetic resonance imaging for pretreatment. Diffusion-weighted magnetic resonance imaging of the lesions revealed a high-signal intensity area, and the apparent diffusion coefficient value of the lesion was 0.61 × 10− 3 mm2s− 1. A partial biopsy of the maxillary region was performed. A diagnosis of Epstein-Barr virus-positive diffuse large B-cell lymphoma was made on the basis of immunohistochemical staining. The patient was transferred to another hospital for treatment. Conclusion This case demonstrates that diffusion-weighted magnetic resonance imaging and immunohistochemistry may be essential for diagnosing Epstein-Barr virus-positive diffuse large B-cell lymphoma.
SN  - 2090-8539
SN  - 1012-5574
ER  -