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Peer-reviewedCC BYJournal of Clinical Medicine

Advancing Genitourinary Cancer Surgery: The Role of Artificial Intelligence and Robotics

4 affiliations
  1. 1Second Department of Urology, National and Kapodistrian University of Athens, Sismanogleio Hospital, 15126 Athens, Greece
  2. 2First Department of Urology, Metropolitan General Hospital, 15562 Athens, Greece
  3. 3Third Department of Urology, Mitera Hospital, 15123 Athens, Greece
  4. 4Department of Urology, University of Patras Hospital, 26504 Patras, Greece

Abstract

The convergence of artificial intelligence and robotic surgery is redefining the management of genitourinary cancers by enhancing diagnostic accuracy, surgical precision, and training efficiency. This narrative review explores recent advancements in artificial intelligence applications across the cancer care continuum, with a focus on prostate, kidney, and bladder malignancies. Artificial intelligence tools, particularly those based on machine learning and deep learning, have demonstrated strong performance in analyzing imaging data, segmenting tumors, predicting pathological features, and supporting clinical decision-making. Intraoperatively, artificial intelligence enables skill assessment, personalized feedback, and real-time navigation by processing data from surgical videos and robotic system sensors. Augmented reality and intraoperative modeling further enhance visualization and margin control during complex procedures. The review also discusses emerging technologies such as single-port robotic platforms, which offer advantages in confined anatomical spaces and support less invasive approaches. Additionally, the growing field of telesurgery is addressed, highlighting its feasibility for complex urologic operations across vast distances. While many of these innovations are still in early stages of clinical validation, their integration into practice has the potential to improve oncologic and functional outcomes, expand access to expert care, and foster the development of next-generation surgical strategies in urologic oncology.

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BibTeX
@article{katsimperis2026advancing,
  title = {{Advancing Genitourinary Cancer Surgery: The Role of Artificial Intelligence and Robotics}},
  author = {Stamatios N. Katsimperis and Νικόλαος Κωστακόπουλος and Themistoklis Ch. Bellos and Theodoros Spinos and Angelis Peteinaris and Lazaros I. Tzelves and A. Kostakopoulos and Andreas A. Skolarikos},
  journal = {Journal of Clinical Medicine},
  year = {2026},
  month = may,
  doi = {10.3390/jcm15103856},
  url = {https://doi.org/10.3390/jcm15103856},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Advancing Genitourinary Cancer Surgery: The Role of Artificial Intelligence and Robotics
AU  - Stamatios N. Katsimperis
AU  - Νικόλαος Κωστακόπουλος
AU  - Themistoklis Ch. Bellos
AU  - Theodoros Spinos
AU  - Angelis Peteinaris
AU  - Lazaros I. Tzelves
AU  - A. Kostakopoulos
AU  - Andreas A. Skolarikos
PY  - 2026
DA  - 2026/05/17
JO  - Journal of Clinical Medicine
DO  - 10.3390/jcm15103856
UR  - https://doi.org/10.3390/jcm15103856
AB  - The convergence of artificial intelligence and robotic surgery is redefining the management of genitourinary cancers by enhancing diagnostic accuracy, surgical precision, and training efficiency. This narrative review explores recent advancements in artificial intelligence applications across the cancer care continuum, with a focus on prostate, kidney, and bladder malignancies. Artificial intelligence tools, particularly those based on machine learning and deep learning, have demonstrated strong performance in analyzing imaging data, segmenting tumors, predicting pathological features, and supporting clinical decision-making. Intraoperatively, artificial intelligence enables skill assessment, personalized feedback, and real-time navigation by processing data from surgical videos and robotic system sensors. Augmented reality and intraoperative modeling further enhance visualization and margin control during complex procedures. The review also discusses emerging technologies such as single-port robotic platforms, which offer advantages in confined anatomical spaces and support less invasive approaches. Additionally, the growing field of telesurgery is addressed, highlighting its feasibility for complex urologic operations across vast distances. While many of these innovations are still in early stages of clinical validation, their integration into practice has the potential to improve oncologic and functional outcomes, expand access to expert care, and foster the development of next-generation surgical strategies in urologic oncology.
SN  - 2077-0383
ER  -