Contrast-Enhanced Ultrasonography of Orbital and Intraocular Pathologies in 24 Dogs and 6 Cats.
6 affiliations
- 1Ophthalmology Unit, Department of Companion Animals and Horses, University of Veterinary Medicine, Vienna, Austria.
- 2Diagnostic Imaging, Department of Companion Animals and Horses, University of Veterinary Medicine, Vienna, Austria.
- 3Tierklinik Neustädter Bucht, Sierksdorf, Germany.
- 4Tierarztpraxis Schönhoff, Stendal, Germany.
- 5Tierklinik Lüsche im SANAKENA, Appen-Etz, Germany.
- 6Pferdeklinik Bargteheide, Bargteheide, Germany.
Abstract
Objective
Contrast-enhanced ultrasonography (CEUS) is a noninvasive and relatively safe imaging technique to assess ocular perfusion, showing high sensitivity and specificity for tumor characterization in human oncology, while reports on its application in canine and feline diseased eyes are limited. This study aimed to describe the CEUS features of orbital and intraocular pathologies in dogs and cats in order to evaluate its diagnostic value in detecting and characterizing various lesions.Animal studied
CEUS examinations of 30 animals (24 dogs, 6 cats) were evaluated retrospectively.Procedures
Following B-mode ultrasonography, CEUS examinations utilizing sulfur hexafluoride were performed. Pathologies were categorized in one of the following groups: orbital neoplastic lesions, orbital inflammatory lesions, intraocular neoplastic lesions, intraocular inflammatory lesions and retinal detachment. Qualitative perfusion parameters, contrast intensity, enhancement pattern, perfusion type and time to wash-in and wash-out were evaluated.Results
CEUS detected vascularization in orbital and intraocular pathologies, with variable enhancement characteristics. Persistent vascularization was observed in all cases of retinal detachment. In orbital and intraocular neoplastic lesions, CEUS improved lesion localization, assessment of interactions with surrounding tissues and tissue perfusion. For inflammatory pathologies such as abscesses, myositis, and steatitis, the additional diagnostic value of CEUS compared to B-mode ultrasonography was limited.Conclusion
Findings indicated that CEUS could identify a variety of orbital and intraocular pathologies and provided additional diagnostic information to B-mode ultrasonography, particularly for assessing neoplastic lesions and retinal detachments. CEUS has the potential to enhance ophthalmic ultrasonography in differentiating specific pathologies. Prospective studies are warranted to further evaluate its clinical use.
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BibTeX
@article{ortner2026contrastenhanced,
title = {{Contrast-Enhanced Ultrasonography of Orbital and Intraocular Pathologies in 24 Dogs and 6 Cats.}},
author = {Janneke I Ortner and Katharina M Hittmair and Barbara Nell and Klaas-Ole Blohm},
journal = {Veterinary ophthalmology},
year = {2026},
month = oct,
doi = {10.1111/vop.70281},
url = {https://europepmc.org/article/MED/42897728},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Contrast-Enhanced Ultrasonography of Orbital and Intraocular Pathologies in 24 Dogs and 6 Cats.
AU - Janneke I Ortner
AU - Katharina M Hittmair
AU - Barbara Nell
AU - Klaas-Ole Blohm
PY - 2026
DA - 2026/10/30
JO - Veterinary ophthalmology
DO - 10.1111/vop.70281
UR - https://europepmc.org/article/MED/42897728
AB - Objective Contrast-enhanced ultrasonography (CEUS) is a noninvasive and relatively safe imaging technique to assess ocular perfusion, showing high sensitivity and specificity for tumor characterization in human oncology, while reports on its application in canine and feline diseased eyes are limited. This study aimed to describe the CEUS features of orbital and intraocular pathologies in dogs and cats in order to evaluate its diagnostic value in detecting and characterizing various lesions.Animal studied CEUS examinations of 30 animals (24 dogs, 6 cats) were evaluated retrospectively.Procedures Following B-mode ultrasonography, CEUS examinations utilizing sulfur hexafluoride were performed. Pathologies were categorized in one of the following groups: orbital neoplastic lesions, orbital inflammatory lesions, intraocular neoplastic lesions, intraocular inflammatory lesions and retinal detachment. Qualitative perfusion parameters, contrast intensity, enhancement pattern, perfusion type and time to wash-in and wash-out were evaluated.Results CEUS detected vascularization in orbital and intraocular pathologies, with variable enhancement characteristics. Persistent vascularization was observed in all cases of retinal detachment. In orbital and intraocular neoplastic lesions, CEUS improved lesion localization, assessment of interactions with surrounding tissues and tissue perfusion. For inflammatory pathologies such as abscesses, myositis, and steatitis, the additional diagnostic value of CEUS compared to B-mode ultrasonography was limited.Conclusion Findings indicated that CEUS could identify a variety of orbital and intraocular pathologies and provided additional diagnostic information to B-mode ultrasonography, particularly for assessing neoplastic lesions and retinal detachments. CEUS has the potential to enhance ophthalmic ultrasonography in differentiating specific pathologies. Prospective studies are warranted to further evaluate its clinical use.
SN - 1463-5216
SN - 1463-5224
ER -