Hi-C data from the filamentous fungus Podospora anserina and associated 3D models to visualize the spatial organization of its chromosomes
- 1Universite Paris Saclay
Abstract
Objectives: Model species are essential for fundamental research in biology. While a complete genomic sequence is a prerequisite for genetic studies, it is not enough on its own. Understanding the three-dimensional organization of the genome is also important, allowing researchers to gain a more realistic understanding of the mechanisms governing genome function. In the fungal model Podospora anserina, although the genomic sequence has been established for a long time, the three-dimensionalorganization remained unknown. Here we obtained the first Hi-C datasets and present associated 3D models, providing the research community with a valuable resource for better multi-omics data integration. Data description: Hi-C experiments were performed in duplicate, using nuclei purified from wild-type fungal mycelium. Four FASTQ files were obtained (two per replicate) and used as inputs for the 3DGB workflow with four different output resolutions, to observe the genome organization of P. anserina at different levels of detail (50 kb, 20 kb, 10 kb, and 5 kb). In a context where researchers already have, for this species, a large amount of traditional omics data (ChIP-seq, RNA-seq, etc.), these 3D models are helpful for complementing the linear representation of the genome, which is traditionally used in bioinformatic analyses.
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BibTeX
@misc{royer2026data,
title = {{Hi-C data from the filamentous fungus Podospora anserina and associated 3D models to visualize the spatial organization of its chromosomes}},
author = {G. Royer and A. Gualdoni and P. Poulain and F. Dumetz and N. Ponts and P. Grognet and F. Malagnac and G. Lelandais},
howpublished = {bioRxiv},
year = {2026},
month = jun,
doi = {10.64898/2026.06.14.732207},
url = {https://www.biorxiv.org/content/10.64898/2026.06.14.732207v2},
note = {CC BY},
}
RIS
TY - UNPB
TI - Hi-C data from the filamentous fungus Podospora anserina and associated 3D models to visualize the spatial organization of its chromosomes
AU - G. Royer
AU - A. Gualdoni
AU - P. Poulain
AU - F. Dumetz
AU - N. Ponts
AU - P. Grognet
AU - F. Malagnac
AU - G. Lelandais
PY - 2026
DA - 2026/06/14
PB - bioRxiv
DO - 10.64898/2026.06.14.732207
UR - https://www.biorxiv.org/content/10.64898/2026.06.14.732207v2
AB - Objectives: Model species are essential for fundamental research in biology. While a complete genomic sequence is a prerequisite for genetic studies, it is not enough on its own. Understanding the three-dimensional organization of the genome is also important, allowing researchers to gain a more realistic understanding of the mechanisms governing genome function. In the fungal model Podospora anserina, although the genomic sequence has been established for a long time, the three-dimensionalorganization remained unknown. Here we obtained the first Hi-C datasets and present associated 3D models, providing the research community with a valuable resource for better multi-omics data integration. Data description: Hi-C experiments were performed in duplicate, using nuclei purified from wild-type fungal mycelium. Four FASTQ files were obtained (two per replicate) and used as inputs for the 3DGB workflow with four different output resolutions, to observe the genome organization of P. anserina at different levels of detail (50 kb, 20 kb, 10 kb, and 5 kb). In a context where researchers already have, for this species, a large amount of traditional omics data (ChIP-seq, RNA-seq, etc.), these 3D models are helpful for complementing the linear representation of the genome, which is traditionally used in bioinformatic analyses.
ER -