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Peer-reviewedCC BY 4.0Frontiers in Psychiatry

Perceived stress, occupational burnout, and anxiety among PIVAS healthcare professionals: the moderating role of research competence

  • QiuRong Chen1,2
  • Chunsong Yang2,3
  • Le Yang4
4 affiliations
  1. 1Department of Hematology Nursing, West China Second University Hospital, Sichuan University
  2. 2Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education
  3. 3Department of Pharmacy, Evidence-based Pharmacy Center, West China Second Hospital, Sichuan University
  4. 4School of Marxism, Sichuan University
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Abstract

Background: Pharmacy Intravenous Admixture Services (PIVAS) are now an integral part of patient care in modern hospitals. However, personnel working in PIVAS are often exposed to intense perceived stress, making them more susceptible to occupational burnout and anxiety, which may negatively impact their physical and mental health, as well as job performance. This study aims to explore the relationships between perceived stress, occupational burnout, research competence, and anxiety.

Methods: A multicenter cross-sectional survey was conducted among PIVAS nurses and pharmacists from hospitals. Data were collected using a structured questionnaire that included sociodemographic information, work experience, perceived stress, and related psychological parameters. Structural equation modeling (SEM) was used to examine the hypothesized direct and indirect relationships among perceived stress, occupational burnout, and anxiety, and to assess the moderating role of research competence.

Results: A total of 609 healthcare professionals from 137 medical institutions in 20 provinces across China participated in the analysis, including 61.6% (375/609) nurses and 38.4% (234/609) pharmacists. 40.9% of participants exhibited symptoms of anxiety. SEM analysis revealed that perceived stress was significantly and positively associated with occupational burnout (z = 6.08, p < 0.05) and anxiety (z = 7.59, p < 0.05), with burnout showing direct and indirect effects within the hypothesized model. Moreover, research competence acted as a positive moderator in the relationships between perceived stress and occupational burnout, perceived stress and anxiety, as well as burnout and anxiety.

Conclusion: Occupational burnout, anxiety, and perceived stress are common among PIVAS nurses and pharmacists. The findings highlight that perceived stress is significantly associated with higher levels of burnout and anxiety symptoms. Notably, research competence moderated these associations. Healthcare institutions should prioritize effective stress management strategies, enhance employees’ research competence, and provide psychological support to mitigate the association between perceived stress and mental health. Future studies should explore the causal relationships between these variables and investigate targeted intervention approaches.

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Cite

BibTeXRIS
BibTeX
@article{chen2026perceived,
  title = {{Perceived stress, occupational burnout, and anxiety among PIVAS healthcare professionals: the moderating role of research competence}},
  author = {QiuRong Chen and Chunsong Yang and Le Yang},
  journal = {Frontiers in Psychiatry},
  year = {2026},
  month = nov,
  doi = {10.3389/fpsyt.2026.1976604},
  url = {https://www.frontiersin.org/articles/10.3389/fpsyt.2026.1976604/full},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Perceived stress, occupational burnout, and anxiety among PIVAS healthcare professionals: the moderating role of research competence
AU  - QiuRong Chen
AU  - Chunsong Yang
AU  - Le Yang
PY  - 2026
DA  - 2026/11/10
JO  - Frontiers in Psychiatry
DO  - 10.3389/fpsyt.2026.1976604
UR  - https://www.frontiersin.org/articles/10.3389/fpsyt.2026.1976604/full
AB  - Background: Pharmacy Intravenous Admixture Services (PIVAS) are now an integral part of patient care in modern hospitals. However, personnel working in PIVAS are often exposed to intense perceived stress, making them more susceptible to occupational burnout and anxiety, which may negatively impact their physical and mental health, as well as job performance. This study aims to explore the relationships between perceived stress, occupational burnout, research competence, and anxiety.  Methods: A multicenter cross-sectional survey was conducted among PIVAS nurses and pharmacists from hospitals. Data were collected using a structured questionnaire that included sociodemographic information, work experience, perceived stress, and related psychological parameters. Structural equation modeling (SEM) was used to examine the hypothesized direct and indirect relationships among perceived stress, occupational burnout, and anxiety, and to assess the moderating role of research competence.  Results: A total of 609 healthcare professionals from 137 medical institutions in 20 provinces across China participated in the analysis, including 61.6% (375/609) nurses and 38.4% (234/609) pharmacists. 40.9% of participants exhibited symptoms of anxiety. SEM analysis revealed that perceived stress was significantly and positively associated with occupational burnout (z = 6.08, p < 0.05) and anxiety (z = 7.59, p < 0.05), with burnout showing direct and indirect effects within the hypothesized model. Moreover, research competence acted as a positive moderator in the relationships between perceived stress and occupational burnout, perceived stress and anxiety, as well as burnout and anxiety.  Conclusion: Occupational burnout, anxiety, and perceived stress are common among PIVAS nurses and pharmacists. The findings highlight that perceived stress is significantly associated with higher levels of burnout and anxiety symptoms. Notably, research competence moderated these associations. Healthcare institutions should prioritize effective stress management strategies, enhance employees’ research competence, and provide psychological support to mitigate the association between perceived stress and mental health. Future studies should explore the causal relationships between these variables and investigate targeted intervention approaches.
SN  - 1664-0640
ER  -