Recent Research on Biosensors for Biomarker Detection Related to Neurological Disorders Utilizing Surface Engineering Strategies.
4 affiliations
- 1Department of Biomedical-Chemical Engineering, The Catholic University of Korea, Bucheon-si 14662, Gyeonggi-do, Republic of Korea.
- 2Department of Biotechnology, The Catholic University of Korea, Bucheon-si 14662, Gyeonggi-do, Republic of Korea.
- 3Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
- 4Department of Chemical Engineering, Research Center of Chemical Technology, Hankyong National University, Anseong-si 17579, Gyeonggi-do, Republic of Korea.
Abstract
Surface engineering strategies have been widely used in various technological fields. Particularly, they have been widely utilized in the biosensing field, to improve interfacial properties and facilitate molecular recognition. Among the various targets of biosensors, in recent years are neurological disorders, which have become a major health challenge globally, increasing the demand for accurate and early detection of neural biomarkers. Despite significant advances in biosensors for the detection of neural biomarkers, traditional biosensors often suffer from low sensitivity and selectivity for the precise detection of neural biomarkers. In this regard, surface engineering strategies hold huge potential and utility to address above issues of biosensors. Therefore, a comprehensive understanding of surface engineering strategies and their impact on neural biosensing is essential for the diagnosis of neurological disorders. In this review, we present recent advances in the development of biosensors for neural biomarker detection that incorporate surface engineering strategies. We first discuss surface engineering strategies applicable in biosensors and their underlying mechanisms. Next, recent surface-engineered biosensors for neural biomarker detection are discussed, configured according to the environmental conditions of biomarkers. We anticipate that this review will provide valuable insights into the development of novel biosensors for the early diagnosis of neurological disorders.
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BibTeX
@article{lee2026recent,
title = {{Recent Research on Biosensors for Biomarker Detection Related to Neurological Disorders Utilizing Surface Engineering Strategies.}},
author = {Yejin Lee and Minji Seo and Sengyeon Pyo and Yumi Kim and Hye Kyu Choi and Minkyu Shin and Jinho Yoon},
journal = {Biosensors},
year = {2026},
month = sep,
doi = {10.3390/bios16100541},
url = {https://europepmc.org/article/MED/42930088},
note = {CC BY},
}
RIS
TY - JOUR
TI - Recent Research on Biosensors for Biomarker Detection Related to Neurological Disorders Utilizing Surface Engineering Strategies.
AU - Yejin Lee
AU - Minji Seo
AU - Sengyeon Pyo
AU - Yumi Kim
AU - Hye Kyu Choi
AU - Minkyu Shin
AU - Jinho Yoon
PY - 2026
DA - 2026/09/28
JO - Biosensors
DO - 10.3390/bios16100541
UR - https://europepmc.org/article/MED/42930088
AB - Surface engineering strategies have been widely used in various technological fields. Particularly, they have been widely utilized in the biosensing field, to improve interfacial properties and facilitate molecular recognition. Among the various targets of biosensors, in recent years are neurological disorders, which have become a major health challenge globally, increasing the demand for accurate and early detection of neural biomarkers. Despite significant advances in biosensors for the detection of neural biomarkers, traditional biosensors often suffer from low sensitivity and selectivity for the precise detection of neural biomarkers. In this regard, surface engineering strategies hold huge potential and utility to address above issues of biosensors. Therefore, a comprehensive understanding of surface engineering strategies and their impact on neural biosensing is essential for the diagnosis of neurological disorders. In this review, we present recent advances in the development of biosensors for neural biomarker detection that incorporate surface engineering strategies. We first discuss surface engineering strategies applicable in biosensors and their underlying mechanisms. Next, recent surface-engineered biosensors for neural biomarker detection are discussed, configured according to the environmental conditions of biomarkers. We anticipate that this review will provide valuable insights into the development of novel biosensors for the early diagnosis of neurological disorders.
SN - 2079-6374
ER -