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Peer-reviewedCC BY 4.0NPJ Systems Biology and Applications

Expanding the role of metabolism in whole plant models

  1. 1School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Thiruvananthapuram, India

Abstract

Whole-plant models capture the dynamics of plant architecture and physiology. However, the representation of metabolism in these frameworks remains limited. This work surveys the representation of metabolism in popular mechanistic whole-plant modelling frameworks. We next discuss the scope of using constraint-based metabolic models to study metabolism at the whole-plant scale and finally present a case for integrating metabolic models with other models to overcome the limitations of individual models.

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BibTeX
@article{shaijal2026expanding,
  title = {{Expanding the role of metabolism in whole plant models}},
  author = {Karuthedath Shaijal and Meera Joshi and Sanu Shameer},
  journal = {NPJ Systems Biology and Applications},
  year = {2026},
  month = jul,
  doi = {10.1038/s41540-026-00773-5},
  url = {https://doi.org/10.1038/s41540-026-00773-5},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Expanding the role of metabolism in whole plant models
AU  - Karuthedath Shaijal
AU  - Meera Joshi
AU  - Sanu Shameer
PY  - 2026
DA  - 2026/07/04
JO  - NPJ Systems Biology and Applications
DO  - 10.1038/s41540-026-00773-5
UR  - https://doi.org/10.1038/s41540-026-00773-5
AB  - Whole-plant models capture the dynamics of plant architecture and physiology. However, the representation of metabolism in these frameworks remains limited. This work surveys the representation of metabolism in popular mechanistic whole-plant modelling frameworks. We next discuss the scope of using constraint-based metabolic models to study metabolism at the whole-plant scale and finally present a case for integrating metabolic models with other models to overcome the limitations of individual models.
SN  - 2056-7189
ER  -